SCHEMBL7329487

SCHEMBL7329487

O=C1c2cccc3cccc(c23)C(=O)N1CCCCO

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HEXA P06865 6/20 0.78
HEXB P07686 6/20 0.78
ALDH1A1 P00352 5/20 0.72
KDM4E B2RXH2 5/20 0.72
KMT2A Q03164 4/20 0.72
MEN1 O00255 3/20 0.72
SMN1; SMN2 Q16637 3/20 0.72
HTT P42858 2/20 0.72
RECQL P46063 2/20 0.72
RAB9A P51151 2/20 0.72
RGS12 O14924 1/20 0.72
NPC1 O15118 1/20 0.72
LMNA P02545 1/20 0.72
PABPC1 P11940 1/20 0.72
GAA P10253 2/20 0.65
HDAC3 O15379 1/20 0.63
LTA4H P09960 1/20 0.63
HDAC4 P56524 1/20 0.63
HDAC1 Q13547 1/20 0.63
HDAC7 Q8WUI4 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11678428 0.98 HEXA (0.76) HEXAHEXBALDH1A1KDM4EKMT2A
SCHEMBL11807201 0.98 HEXA (0.76) HEXAHEXBALDH1A1KDM4EKMT2A
SCHEMBL4187947 0.95 HEXA (0.81) HEXAHEXBALDH1A1KDM4EKMT2A
SCHEMBL9626265 0.91 HEXA (0.83) HEXAHEXBALDH1A1KDM4EKMT2A
SCHEMBL9625779 0.90 HEXA (0.81) HEXAHEXBALDH1A1KDM4EKMT2A
SCHEMBL9625395 0.90 HEXA (0.81) HEXAHEXBALDH1A1KDM4EKMT2A
SCHEMBL9625535 0.90 HEXA (0.81) HEXAHEXBALDH1A1KDM4EKMT2A
SCHEMBL9625518 0.90 HEXA (0.81) HEXAHEXBALDH1A1KDM4EKMT2A
SCHEMBL4997995 0.88 HEXA (1.00) HEXAHEXBALDH1A1KDM4EKMT2A
SCHEMBL17718739 0.85 ALDH1A1 (0.69) HEXAHEXBALDH1A1KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103864685-B A kind of fluorescent probe and the application in detection ferrous ion thereof DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) 2015-10-21 CN claimed
CN-103864685-A Fluorescent probe and application thereof in detection of divalent iron ions DALIAN CHEMICAL PHYSICS INST 2014-06-18 CN claimed
US-4006238-A Use of 2-(hydroxyalkyl)-1H-benz[de]isoquinoline-1,3(2H)-diones as anti-allergy agents E. R. SQUIBB & SONS, INC. (US) 1977-02-01 US claimed
US-20240224999-A1 METABOLIC INHIBITORS FOR CONTROLLING BIOFILM MC US 3 LLC (US) 2024-07-11 US disclosed
US-20240224999-A1 METABOLIC INHIBITORS FOR CONTROLLING BIOFILM MC US 3 LLC (US) 2024-07-11 US disclosed
US-20230183640-A1 METABOLIC INHIBITORS WITH EFFICACY FOR INHIBITING SULFIDE PRODUCTION IN HARSH ENVIRONMENTS LANXESS CORPORATION 2023-06-15 US disclosed
US-20230183640-A1 METABOLIC INHIBITORS WITH EFFICACY FOR INHIBITING SULFIDE PRODUCTION IN HARSH ENVIRONMENTS LANXESS CORPORATION 2023-06-15 US disclosed
EP-0612324-A1 PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY SMITHKLINE BEECHAM PLC (GB) 1994-08-31 EP disclosed
WO-1993009136-A1 PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY SMITHKLINE BEECHAM PLC (GB) 1993-05-13 WO disclosed
US-4077958-A ANTIDEPRESSANTS E. R. SQUIBB & SONS, INC. (US) 1978-03-07 US disclosed
US-4007191-A ANTIDEPRESSANT E. R. SQUIBB & SONS, INC. (US) 1977-02-08 US disclosed
US-4006238-A Use of 2-(hydroxyalkyl)-1H-benz[de]isoquinoline-1,3(2H)-diones as anti-allergy agents E. R. SQUIBB & SONS, INC. (US) 1977-02-01 US disclosed
US-3940397-A ANTIINFLAMMATORY E. R. SQUIBB & SONS, INC. (US) 1976-02-24 US disclosed
US-3935227-A ANTIDEPRESSANTS, ANTIANXIETY, ANTIINFLAMMATORY AGENTS E. R. SQUIBB & SONS, INC. (US) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240224999-A1 METABOLIC INHIBITORS FOR CONTROLLING BIOFILM RIMKLA, HDHD5, SCD HEXA 453/4885HEXB 393/4885ALDH1A1 1413/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.