Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329332 | 0.81 | MEN1 (0.42) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL10473768 | 0.71 | MAP3K5 (0.50) | KMT2A | |
| SCHEMBL7327518 | 0.70 | ALDH1A1 (0.41) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL12685604 | 0.69 | RAB9A (0.53) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7326994 | 0.69 | RAB9A (0.53) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5062569 | 0.69 | ALDH1A1 (0.46) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11755046 | 0.68 | NPC1 (0.47) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11489729 | 0.66 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL11754453 | 0.65 | RAB9A (0.35) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL11484272 | 0.65 | LMNA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102890-A | Anxiolytic agents | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |