Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330327 | 0.90 | SOAT1 (0.32) | — | |
| SCHEMBL7323662 | 0.86 | CTSD (0.34) | SIRT2 | |
| SCHEMBL7332523 | 0.86 | SOAT1 (0.33) | SIRT2ALDH1A1 | |
| SCHEMBL7330215 | 0.85 | CTSL (0.41) | SIRT2CTSLCTSS | |
| SCHEMBL7323101 | 0.80 | SIRT2 (0.33) | SIRT2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7332898 | 0.78 | CTSD (0.33) | — | |
| SCHEMBL9297056 | 0.78 | SIRT2 (0.34) | SIRT2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7332120 | 0.76 | SIRT2 (0.33) | SIRT2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7323558 | 0.76 | SIRT2 (0.33) | SIRT2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7322416 | 0.76 | CTSD (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |