Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 14/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 11/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 8/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324481 | 0.89 | CAPN1 (0.36) | CTSLCTSSSIRT2CAPN1CAPN2 | |
| SCHEMBL7329784 | 0.85 | CTSB (0.42) | CTSLCTSSSIRT2CAPN1CAPN2 | |
| SCHEMBL7323250 | 0.85 | SOAT1 (0.37) | CTSLCTSSSIRT2CAPN1CAPN2 | |
| SCHEMBL7329917 | 0.85 | SIRT2 (0.35) | CTSLCTSSSIRT2 | |
| SCHEMBL7323289 | 0.79 | CTSL (0.41) | CTSLCTSSSIRT2CAPN1CAPN2 | |
| SCHEMBL9296873 | 0.76 | SIRT2 (0.40) | CTSLCTSSSIRT2CAPN1CAPN2 | |
| SCHEMBL7327305 | 0.75 | CTSB (0.40) | SIRT2CAPN1CAPN2SIRT1SIRT3 | |
| SCHEMBL7330327 | 0.74 | SOAT1 (0.32) | — | |
| SCHEMBL7321181 | 0.73 | SIRT2 (0.39) | CTSLCTSSSIRT2CAPN1CAPN2 | |
| SCHEMBL7331504 | 0.73 | SIRT2 (0.38) | CTSLCTSSSIRT2CAPN1CAPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |