Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.31 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.31 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9297056 | 0.86 | SIRT2 (0.34) | SIRT2PPARASOAT1MEN1ALDH1A1 | |
| SCHEMBL7332120 | 0.85 | SIRT2 (0.33) | SIRT2PPARAMEN1ALDH1A1HPGD | |
| SCHEMBL7323558 | 0.85 | SIRT2 (0.33) | SIRT2PPARAMEN1ALDH1A1HPGD | |
| SCHEMBL7333687 | 0.84 | SIRT2 (0.32) | SIRT2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7323289 | 0.84 | CTSL (0.41) | SIRT2CTSLCTSSSIRT1SIRT3 | |
| SCHEMBL7331182 | 0.81 | SOAT1 (0.32) | SOAT1TLR2 | |
| SCHEMBL7329917 | 0.80 | SIRT2 (0.35) | SIRT2MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7328766 | 0.80 | SOAT1 (0.31) | PPARASOAT1 | |
| SCHEMBL7330316 | 0.80 | SOAT1 (0.31) | SOAT1 | |
| SCHEMBL7324588 | 0.77 | CTSD (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |