Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP1 | P07148 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | F2 | P00734 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | BRAF | P15056 | 1/20 | 0.52 |
| ▸ | IL1RN | P18510 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325645 | 0.91 | F2 (0.60) | FABP1MAPK1F2PKMRECQL | |
| SCHEMBL7335570 | 0.90 | CYP19A1 (0.61) | FABP1MAPK1F2PKMRECQL | |
| SCHEMBL7324870 | 0.90 | F2 (0.59) | FABP1F2PKMRECQLHTT | |
| SCHEMBL7324125 | 0.89 | F2 (0.60) | FABP1MAPK1F2PKMRECQL | |
| SCHEMBL7327586 | 0.86 | EPHX2 (0.58) | FABP1MAPK1F2LMNABRAF | |
| SCHEMBL7324171 | 0.85 | NR3C1 (0.61) | ALDH1A1LMNABRAFMEN1MAPT | |
| SCHEMBL7325766 | 0.85 | ALDH1A1 (0.58) | FABP1F2PKMRECQLHTT | |
| SCHEMBL11339354 | 0.84 | MEN1 (0.67) | PKMRECQLHTTALDH1A1TBXA2R | |
| SCHEMBL7330175 | 0.83 | F2 (0.67) | F2PKMRECQLHTTTBXA2R | |
| SCHEMBL7361453 | 0.82 | MAPK1 (0.52) | FABP1MAPK1F2PKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |