Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | FABP1 | P07148 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330777 | 0.83 | PGR (0.58) | MAPK1FABP1TSHRHTTALDH1A1 | |
| SCHEMBL7330191 | 0.82 | FABP1 (0.62) | MAPK1FABP1HTTPKMLMNA | |
| SCHEMBL7324870 | 0.78 | F2 (0.59) | FABP1HTTPKMLMNASMN1; SMN2 | |
| SCHEMBL7324125 | 0.77 | F2 (0.60) | MAPK1FABP1GAAHTTPKM | |
| SCHEMBL7325645 | 0.77 | F2 (0.60) | MAPK1FABP1GAAHTTPKM | |
| SCHEMBL7335570 | 0.76 | CYP19A1 (0.61) | MAPK1FABP1PKMLMNASMN1; SMN2 | |
| SCHEMBL7336019 | 0.74 | BRAF (0.51) | FABP1POLBTSHRHTTSMN1; SMN2 | |
| SCHEMBL8549186 | 0.74 | ACLY (0.44) | POLBGAATSHRIDH1MEN1 | |
| Benzoic Acid SCHEMBL28546974 | 0.74 | TSHR (0.55) | GAATSHRHTTLMNAALDH1A1 | |
| SCHEMBL7325766 | 0.74 | ALDH1A1 (0.58) | FABP1POLBGAAHTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |