Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.56 |
| ▸ | BRAF | P15056 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | FABP1 | P07148 | 1/20 | 0.54 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | IDH1 | O75874 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | CDK7 | P50613 | 1/20 | 0.51 |
| ▸ | CCNH | P51946 | 1/20 | 0.51 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324171 | 0.90 | NR3C1 (0.61) | BRAFKMT2AARMAPTLMNA | |
| SCHEMBL7325645 | 0.88 | F2 (0.60) | FABP1ARLMNAPTPN1FFAR1 | |
| SCHEMBL7330191 | 0.86 | FABP1 (0.62) | BRAFKMT2AFABP1ERAP1MAPT | |
| SCHEMBL7327897 | 0.86 | IDH1 (0.57) | EPHX2ROCK2BRAFKMT2AERAP1 | |
| SCHEMBL7324870 | 0.84 | F2 (0.59) | FABP1MAPTLMNAFFAR1CDK1 | |
| SCHEMBL7335570 | 0.84 | CYP19A1 (0.61) | BRAFFABP1ARLMNAMAPK1 | |
| SCHEMBL7359983 | 0.84 | ROCK2 (0.62) | EPHX2ROCK2KMT2AMAPTLMNA | |
| SCHEMBL9812957 | 0.82 | CYP19A1 (0.67) | KMT2AARLMNAMEN1 | |
| SCHEMBL17468424 | 0.82 | PGR (0.65) | EPHX2BRAFKMT2AERAP1AR | |
| SCHEMBL7324125 | 0.81 | F2 (0.60) | KMT2AFABP1LMNAMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |