Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 3/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7321546 | 0.99 | PDK1 (0.46) | PDK1HRH3MEN1KMT2ATDP1 | |
| SCHEMBL7320345 | 0.80 | CHRM2 (0.44) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7329512 | 0.79 | LMNA (0.46) | MEN1KMT2A | |
| SCHEMBL3221856 | 0.77 | CHRNB4 (0.46) | TDP1DRD4 | |
| SCHEMBL3221893 | 0.77 | CHRNB4 (0.46) | TDP1DRD4 | |
| SCHEMBL3221853 | 0.77 | CHRNB4 (0.46) | TDP1DRD4 | |
| SCHEMBL12200223 | 0.75 | HTR1B (0.53) | HRH3MEN1KMT2ATDP1DRD4 | |
| SCHEMBL16902861 | 0.75 | HTR1B (0.53) | HRH3MEN1KMT2ATDP1DRD4 | |
| SCHEMBL7329686 | 0.72 | SLC18A2 (0.52) | — | |
| SCHEMBL7328652 | 0.72 | LTA4H (0.46) | HRH3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625979-A1 | AZABRICYCLIC COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-11-30 | — | — | EP | claimed |
| WO-1993015073-A1 | AZABRICYCLIC COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-08-05 | — | — | WO | claimed |