SCHEMBL733036

SCHEMBL733036

O=C(O)c1cc(B(O)O)ccc1F

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
ASPH Q12797 1/20 0.44
KDM8 Q8N371 1/20 0.44
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
CYP3A4 P08684 1/20 0.41
ALB P02768 1/20 0.38
MRGPRX4 Q96LA9 1/20 0.38
KEAP1 Q14145 1/20 0.37
LMNA P02545 1/20 0.37
AKR1C2 P52895 1/20 0.37
AKR1C1 Q04828 1/20 0.37
TTR P02766 2/20 0.37
ENPP2 Q13822 1/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
MAP2K2 P36507 1/20 0.36
MAP2K1 Q02750 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29825352 1.00 KDM4E (0.44) KDM4EASPHKDM8CES2CES1
SCHEMBL29689051 0.84 CES2 (0.41) KDM4EASPHKDM8CES2CES1
SCHEMBL362047 0.84 CES2 (0.41) KDM4EASPHKDM8CES2CES1
SCHEMBL790041 0.82 DGAT1 (0.43) KDM4ECES2CES1ENPP2CA1
SCHEMBL4847318 0.82 CES2 (0.39) CES2CES1ENPP2CA1CA2
SCHEMBL24137921 0.82 ALDH1A1 (0.48) KDM4ECES2CES1TTRENPP2
SCHEMBL29116266 0.81 NOTUM (0.43) CYP3A4MRGPRX4TTR
SCHEMBL918043 0.81 ALDH1A1 (0.44) KDM4ETTRENPP2CA1CA2
SCHEMBL30807652 0.81 ALDH1A1 (0.44) KDM4ETTRENPP2CA1CA2
SCHEMBL14920414 0.80 KDM4E (0.39) KDM4EASPHKDM8CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
CN-119081158-A Preparation method of bio-based wet adhesion hydrogel 中国海洋大学 2024-12-06 CN claimed
CN-114805856-B Injectable pH/ROS dual-response hydrogel and preparation method and application thereof 天津大学 2024-11-22 CN claimed
CN-118620062-A Phenylboronic acid modified albumin carrier and application thereof 中国药科大学 2024-09-10 CN claimed
CN-118001218-A Blood sugar response type drug release visual long-acting microneedle and preparation method thereof 沈阳药科大学 2024-05-10 CN claimed
US-11931454-B2 Wet-packed soft hydrogel ocular inserts ALCON INC. (CH) 2024-03-19 US claimed
US-20230380457-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-30 US claimed
EP-4280882-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2023-11-29 EP claimed
US-20230363426-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-16 US claimed
US-20220264914-A1 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. 2022-08-25 US claimed
CN-114805856-A Injectable pH/ROS dual-response hydrogel and preparation method and application thereof 天津大学 2022-07-29 CN claimed
US-20220225646-A1 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. 2022-07-21 US claimed
US-20220225647-A1 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. 2022-07-21 US claimed
CN-114727954-A Wet packed soft hydrogel ocular inserts 爱尔康公司 2022-07-08 CN claimed
EP-4017478-A1 WET-PACKED SOFT HYDROGEL OCULAR INSERTS Alcon Inc. (CH) 2022-06-29 EP claimed
CN-114585396-A Injectable hydrogel with anti-inflammatory and repair promoting functions, preparation method thereof and application thereof in heart repair 四川大学 2022-06-03 CN claimed
CN-112679535-A Small molecule PAD4 inhibitor and preparation method and application thereof 首都医科大学 2021-04-20 CN claimed
WO-2021053586-A1 WET-PACKED SOFT HYDROGEL OCULAR INSERTS ALCON INC. (CH) 2021-03-25 WO claimed
US-20210077385-A1 WET-PACKED SOFT HYDROGEL OCULAR INSERTS ALCON INC. (CH) 2021-03-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210077385-A1 WET-PACKED SOFT HYDROGEL OCULAR INSERTS BRI3BP, BRWD1, HRH2 KDM4E 2965/4885ASPH 71/4885KDM8 2089/4885
US-11931454-B2 Wet-packed soft hydrogel ocular inserts BRI3BP, BRWD1, HRH2 KDM4E 2965/4885ASPH 71/4885KDM8 2089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.