SCHEMBL362047

SCHEMBL362047

O=C(O)c1ccc(B(O)O)cc1F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
KDM4E B2RXH2 1/20 0.40
ASPH Q12797 1/20 0.40
KDM8 Q8N371 1/20 0.40
RARB P10826 3/20 0.40
RARA P10276 2/20 0.40
RARG P13631 1/20 0.40
CYP1A2 P05177 1/20 0.39
ALB P02768 1/20 0.38
KEAP1 Q14145 2/20 0.37
EPHX2 P34913 1/20 0.37
NR1H4 Q96RI1 1/20 0.37
AKR1C2 P52895 1/20 0.37
AKR1C1 Q04828 1/20 0.37
TTR P02766 1/20 0.37
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA12 O43570 1/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29689051 1.00 CES2 (0.41) CES2CES1KDM4EASPHKDM8
SCHEMBL733036 0.84 KDM4E (0.44) CES2CES1KDM4EASPHKDM8
SCHEMBL29825352 0.84 KDM4E (0.44) CES2CES1KDM4EASPHKDM8
SCHEMBL290252 0.82 DGAT1 (0.56) CES2CES1KDM4ETTRCA1
SCHEMBL30963904 0.82 MAOB (0.43) CES2CES1CA1CA2ALDH1A1
SCHEMBL29951442 0.82 DGAT1 (0.56) CES2CES1KDM4ETTRCA1
SCHEMBL1319282 0.82 MAOB (0.43) CES2CES1CA1CA2ALDH1A1
SCHEMBL13644473 0.82 ALDH1A1 (0.48) CES2CES1KDM4ETTRCA1
SCHEMBL918043 0.81 ALDH1A1 (0.44) KDM4ECYP1A2TTRCA1CA2
SCHEMBL30807652 0.81 ALDH1A1 (0.44) KDM4ECYP1A2TTRCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 598 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250206879-A1 BORONIC ACID-CONTAINING MODIFIED POLYROTAXANE NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2025-06-26 US claimed
CN-120154570-A Injectable responsive multifunctional hydrogels and uses thereof 浙江大学医学院附属邵逸夫医院 2025-06-17 CN claimed
CN-119823163-A Small molecular boron-10 carrying agent, preparation method and application 东莞市人民医院 2025-04-15 CN claimed
WO-2025031391-A1 SUGAR-RESPONSIVE PROTAMINE INSULIN, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江大学 2025-02-13 WO claimed
EP-4497476-A1 BORONIC ACID-CONTAINING MODIFIED POLYROTAXANE National University Corporation Kumamoto University (JP) 2025-01-29 EP claimed
CN-118847478-B Stainless steel belt for high-flatness automobile decoration and preparation process thereof 江苏甬金金属科技有限公司 2024-12-17 CN claimed
CN-114805856-B Injectable pH/ROS dual-response hydrogel and preparation method and application thereof 天津大学 2024-11-22 CN claimed
CN-118847478-A Stainless steel belt for high-flatness automobile decoration and preparation process thereof 江苏甬金金属科技有限公司 2024-10-29 CN claimed
US-12121611-B2 Oral care composition, and preparation method and application thereof WUHAN UNIVERSITY (CN) 2024-10-22 US claimed
CN-118620062-A Phenylboronic acid modified albumin carrier and application thereof 中国药科大学 2024-09-10 CN claimed
WO-2021126970-A1 SEQUENTIAL TARGETING IN CROSSLINKING NANO-THERANOSTICS FOR TREATING BRAIN TUMORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-06-24 WO claimed
CN-112898579-A High polymer material, mixed micelle, preparation method and application thereof 四川大学 2021-06-04 CN claimed
CN-112521412-A Preparation method of conductive polymer for specifically recognizing glucose and glucose sensor 内蒙古民族大学 2021-03-19 CN claimed
CN-112315940-A Nanoparticle for promoting tumor coagulation and enzyme/ATP dual-responsive drug release, and preparation method and application thereof 暨南大学 2021-02-05 CN claimed
CN-112206219-A Preparation and application of glucose-sensitive insulin delivery system 沈阳药科大学 2021-01-12 CN claimed
CN-111424429-A Metal sulfide porous framework material, and preparation method and application thereof 山东交通学院 2020-07-17 CN claimed
CN-108079282-B Gold nanocluster particles capable of intelligently releasing insulin to regulate blood sugar and preparation method of gold nanocluster particles 武汉大学 2020-06-09 CN claimed
CN-111162313-A Polymer electrolyte and lithium ion battery 珠海冠宇电池有限公司 2020-05-15 CN claimed
CN-111138687-A Injectable glucose response self-healing hydrogel and preparation method and application thereof 中国药科大学 2020-05-12 CN claimed
CN-110564669-A auxiliary platform for transferring exogenous molecules to cells and preparation method and application thereof 苏州大学 2019-12-13 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12121611-B2 Oral care composition, and preparation method and application thereof TAF1, TAF9, TBCA CES2 2729/4885CES1 2809/4885KDM4E 2988/4885
US-20250206879-A1 BORONIC ACID-CONTAINING MODIFIED POLYROTAXANE BTD, CLTB, BTN3A1 CES2 500/4885CES1 1201/4885KDM4E 4097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.