Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5023442 | 0.73 | FDPS (0.38) | LMNAHSD17B10FDPSMMP9MMP13 | |
| SCHEMBL12662196 | 0.73 | FDPS (0.43) | LMNAHSD17B10FDPS | |
| SCHEMBL14572989 | 0.71 | LMNA (0.41) | CA2CA1LMNAHSD17B10FDPS | |
| SCHEMBL2304603 | 0.71 | LMNA (0.41) | CA2CA1LMNAHSD17B10FDPS | |
| Hydrochloric Acid SCHEMBL5195847 | 0.71 | FDPS (0.41) | LMNAHSD17B10FDPS | |
| SCHEMBL27877312 | 0.71 | LMNA (0.41) | CA2CA1LMNAHSD17B10FDPS | |
| SCHEMBL27978703 | 0.70 | ALDH1A1 (0.32) | LMNAHSD17B10FDPSMMP9MMP13 | |
| SCHEMBL7419895 | 0.70 | LMNA (0.34) | CA12CA14CA2CA1LMNA | |
| SCHEMBL7419892 | 0.70 | LMNA (0.34) | CA12CA14CA2CA1LMNA | |
| SCHEMBL23089887 | 0.69 | FDPS (0.35) | LMNAHSD17B10FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494925-A | TREATING DEGENERATIVE DISORDERS; PROTEOLYTIC ENZYME INHIBITOR | STERLING WINTHROP INC. (US) | 1996-02-27 | — | — | US | disclosed |