Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | HTR1A | P08908 | 2/20 | 0.66 |
| ▸ | HTR2A | P28223 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | MPO | P05164 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | HTR1D | P28221 | 1/20 | 0.60 |
| ▸ | HTR1B | P28222 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | SNCA | P37840 | 1/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6922503 | 0.83 | CYP1A2 (0.70) | KDM4EHTR1AALDH1A1MPOMEN1 | |
| SCHEMBL24453252 | 0.81 | HTR2C (0.62) | CYP2D6HTR2CTRPV1FAAHCDK4 | |
| SCHEMBL2536567 | 0.81 | LTA4H (0.67) | KDM4EHTR1AHTR2AMPOCYP2D6 | |
| SCHEMBL25493845 | 0.80 | NR4A2 (0.55) | TRPV1FAAHLTA4HPLA2G2A | |
| SCHEMBL7323553 | 0.80 | HTR1D (0.68) | HTR1AHTR2AMPOCYP2D6HTR2C | |
| SCHEMBL29385251 | 0.80 | HTR2A (1.00) | KDM4EHTR1AHTR2AALDH1A1HTT | |
| SCHEMBL379409 | 0.80 | HTR2A (1.00) | KDM4EHTR1AHTR2AALDH1A1HTT | |
| SCHEMBL4303662 | 0.79 | KDM4E (0.70) | KDM4EHTR1AHTR2AALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL2684408 | 0.79 | HTR2A (0.97) | KDM4EHTR1AHTR2AALDH1A1HTT | |
| SCHEMBL10648384 | 0.78 | CHRNB2 (0.78) | KDM4EHTR1AHTR2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674620-A1 | TRYPTAMINE ANALOGUES AS 5-HT 1?-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-10-04 | — | — | EP | claimed |
| WO-1994014771-A1 | TRYPTAMINE ANALOGUES AS 5-HT1-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-07-07 | — | — | WO | claimed |
| EP-0674620-A1 | TRYPTAMINE ANALOGUES AS 5-HT 1?-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014771-A1 | TRYPTAMINE ANALOGUES AS 5-HT1-LIKE AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-07-07 | — | — | WO | disclosed |