Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.70 |
| ▸ | BLM | P54132 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | PKM | P14618 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | MTNR1A | P48039 | 12/20 | 0.69 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.69 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | IDO1 | P14902 | 1/20 | 0.69 |
| ▸ | SPR | P35270 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921195 | 0.87 | MTNR1A (0.82) | CYP1A2BLMMEN1KMT2AMTNR1A | |
| SCHEMBL7334188 | 0.84 | TRPV1 (0.65) | MTNR1AMTNR1BIDO1TRPV1FAAH | |
| SCHEMBL7022005 | 0.83 | MTNR1A (0.65) | CYP1A2BLMMEN1KMT2ALMNA | |
| SCHEMBL6923141 | 0.83 | ICMT (0.67) | CYP1A2BLMMEN1KMT2ALMNA | |
| SCHEMBL1774144 | 0.83 | CYP1A2 (0.67) | CYP1A2BLMMEN1KMT2ALMNA | |
| SCHEMBL7330504 | 0.83 | KDM4E (0.66) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| Nb-Acetyltryptamine SCHEMBL468850 | 0.83 | MEN1 (1.00) | CYP1A2BLMMEN1KMT2ALMNA | |
| SCHEMBL7015300 | 0.82 | MTNR1A (0.62) | CYP1A2BLMMEN1KMT2ALMNA | |
| SCHEMBL31543720 | 0.82 | MTNR1A (0.72) | CYP1A2BLMMEN1KMT2ALMNA | |
| SCHEMBL8285865 | 0.82 | MTNR1A (0.72) | CYP1A2BLMMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004085392-A1 | MELATONIN DERIVATIVES AND THEIR USE FOR TREATING NEUROLOGICAL DYSFUNCTIONS | FAUST PHARMACEUTICALS (FR) | 2004-10-07 | — | — | WO | disclosed |