SCHEMBL733057

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28451770	0.96	PDE4A (0.41)	CA1CA2CA4CA7CA9
	SCHEMBL732633	0.88	KMT2A (0.39)	PDE4BPDE4APDE4CPDE4DKMT2A
	SCHEMBL16720145	0.87	PDE4B (0.46)	CA1CA2CA4CA7CA9
	SCHEMBL730845	0.85	ALDH1A1 (0.42)	PDE4BPDE4APDE4CPDE4DALDH1A1
	SCHEMBL730813	0.82	PDE4A (0.36)	PDE4BPDE4APDE4CPDE4DKMT2A
	Water SCHEMBL28136778	0.82	CA1 (0.55)	CA1CA2CA4CA7CA9
	SCHEMBL733076	0.81	ACHE (0.40)	KMT2AMEN1MAPTALDH1A1HPGD
	SCHEMBL730765	0.81	CA12 (0.46)	CA1CA2CA7CA9CA12
	SCHEMBL355567	0.79	CA1 (0.57)	CA1CA2CA4CA7CA9
	SCHEMBL730296	0.79	ERN1 (0.38)	KMT2ATSHRMEN1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.