Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333993 | 0.90 | L3MBTL1 (0.51) | L3MBTL1HTTPOLBNPSR1NPC1 | |
| SCHEMBL7332819 | 0.90 | L3MBTL1 (0.50) | L3MBTL1HTTPOLBNPSR1NPC1 | |
| SCHEMBL7336057 | 0.89 | L3MBTL1 (0.51) | L3MBTL1HTTPOLBNPSR1TDP1 | |
| SCHEMBL7330771 | 0.87 | ATM (0.50) | L3MBTL1HTTPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL7329854 | 0.86 | L3MBTL1 (0.62) | L3MBTL1HTTPOLBNPSR1NPC1 | |
| SCHEMBL7332190 | 0.86 | ATM (0.48) | L3MBTL1HTTPOLBNPSR1NPC1 | |
| SCHEMBL7338009 | 0.85 | KMT2A (0.50) | L3MBTL1HTTPOLBNPSR1NPC1 | |
| SCHEMBL7330045 | 0.80 | KMT2A (0.47) | POLBKMT2AMRGPRX4ATM | |
| SCHEMBL7336104 | 0.79 | POLB (0.52) | L3MBTL1HTTPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL7335707 | 0.79 | L3MBTL1 (0.50) | L3MBTL1HTTPOLBNPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430047-A | Neurotensin antagonists | WARNER-LAMBERT COMPANY (US) | 1995-07-04 | — | — | US | disclosed |