Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.66 |
| ▸ | ALB | P02768 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromoxynil SCHEMBL19210 | 0.81 | TTR (1.00) | TTRALBMEN1KMT2ACRHBP | |
| Bromoxynil SCHEMBL1701902 | 0.81 | TTR (1.00) | TTRALBMEN1KMT2ACRHBP | |
| Bromoxynil SCHEMBL5148039 | 0.80 | TTR (0.73) | TTRALBMEN1KMT2ACRHBP | |
| Bromoxynil SCHEMBL726301 | 0.79 | TTR (0.95) | TTRALBMEN1KMT2ACRHBP | |
| Bromoxynil SCHEMBL22721314 | 0.79 | TTR (0.95) | TTRALBMEN1KMT2ACRHBP | |
| Bromoxynil SCHEMBL29642876 | 0.79 | TTR (0.95) | TTRALBMEN1KMT2ACRHBP | |
| Bromoxynil SCHEMBL466353 | 0.79 | TTR (0.95) | TTRALBMEN1KMT2ACRHBP | |
| SCHEMBL29392995 | 0.79 | — | — | |
| SCHEMBL27875336 | 0.79 | TSHR (0.50) | MEN1KMT2ACXCR2ESR2PGR | |
| SCHEMBL5756 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138118-B2 | Plant safening agents ; side effect reduction of pesticides, herbicides, insecticides, fungicides | BAYER CROPSCIENCE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-7838463-B2 | Safeners based on acrylic-aliphatic carboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2010-11-23 | — | — | US | disclosed |
| EP-1653804-A1 | USE OF AROMATIC COMPOUNDS AS SAFENERS | Bayer CropScience GmbH (DE) | 2006-05-10 | — | — | EP | disclosed |
| EP-1653806-A1 | SAFENER BASED ON AROMATIC-ALIPHATIC CARBOXYLIC ACID DERIVATIVES | Bayer CropScience GmbH (DE) | 2006-05-10 | — | — | EP | disclosed |
| EP-1610611-A1 | USE OF AROMATIC HYDROXY COMPOUNDS AS SAFENERS | Bayer CropScience GmbH (DE) | 2006-01-04 | — | — | EP | disclosed |
| US-20050049145-A1 | Safeners based on acrylic-aliphatic carboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2005-03-03 | — | — | US | disclosed |
| WO-2005016001-A1 | SAFENER BASED ON AROMATIC-ALIPHATIC CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE GMBH (DE) | 2005-02-24 | — | — | WO | disclosed |
| WO-2005015994-A1 | USE OF AROMATIC COMPOUNDS AS SAFENERS | BAYER CROPSCIENCE GMBH (DE) | 2005-02-24 | — | — | WO | disclosed |
| US-20050037922-A1 | Use of hydroxyaromatics as safeners | BAYER CROPSCIENCE GMBH (DE) | 2005-02-17 | — | — | US | disclosed |
| US-20040224844-A1 | Use of hydroxyaromatic compounds as safeners | BAYER CROPSCIENCE GMBH (DE) | 2004-11-11 | — | — | US | disclosed |
| WO-2004084631-A1 | USE OF AROMATIC HYDROXY COMPOUNDS AS SAFENERS | BAYER CROPSCIENCE GMBH (DE) | 2004-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050037922-A1 | Use of hydroxyaromatics as safeners | CBR1, CYP8B1, AHR | TTR 1492/4885ALB 1836/4885MEN1 4848/4885 |
| US-20050049145-A1 | Safeners based on acrylic-aliphatic carboxylic acid derivatives | GRHPR, HCAR1, HCAR3 | TTR 2233/4885ALB 1420/4885MEN1 4289/4885 |
| US-20040224844-A1 | Use of hydroxyaromatic compounds as safeners | CBR1, CYC1, NR2E1 | TTR 2819/4885ALB 3832/4885MEN1 4748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.