Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.62 |
| ▸ | PLAAT3 | P53816 | 3/20 | 0.57 |
| ▸ | PLAAT5 | Q96KN8 | 3/20 | 0.57 |
| ▸ | PLAAT2 | Q9NWW9 | 3/20 | 0.57 |
| ▸ | PLAAT4 | Q9UL19 | 3/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304796 | 0.88 | L3MBTL1 (0.55) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL2773677 | 0.85 | FFAR1 (0.66) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL9725829 | 0.85 | FFAR1 (0.65) | FFAR1FFAR4EPHX2 | |
| Alcohol SCHEMBL28404120 | 0.84 | L3MBTL1 (0.52) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL7060212 | 0.83 | F2RL1 (0.58) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL7270063 | 0.81 | FFAR1 (0.74) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL9726057 | 0.81 | CYP4F2 (0.53) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL1375513 | 0.80 | CYP4F2 (0.51) | HPGD | |
| SCHEMBL27472366 | 0.79 | ALOX5 (0.61) | FFAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL7061931 | 0.79 | CYP1A2 (0.51) | FFAR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472380-A | CARBOXYALKYL DIPEPTIDE DERIVATIVES | MERCK & CO., INC. (US) | 1984-09-18 | — | — | US | disclosed |
| US-4374829-A | Aminoacid derivatives as antihypertensives | MERCK & CO., INC. (US) | 1983-02-22 | — | — | US | disclosed |
| EP-0012401-A1 | Carboxyalkyl dipeptide derivatives, process for preparing them and pharmaceutical composition containing them | MERCK & CO. INC. (US) | 1980-06-25 | — | — | EP | disclosed |