Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.65 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.65 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304796 | 0.87 | L3MBTL1 (0.55) | FFAR1ALDH1A1L3MBTL1ALOX5TDP1 | |
| SCHEMBL5349028 | 0.86 | NR1H4 (0.64) | FFAR1FFAR4NR1H4ALDH1A1LMNA | |
| SCHEMBL3091164 | 0.86 | FFAR1 (0.68) | FFAR1FFAR4NR1H4ALDH1A1LMNA | |
| SCHEMBL1171712 | 0.85 | NR1H4 (0.60) | NR1H4ALDH1A1LMNAL3MBTL1LTA4H | |
| SCHEMBL7330817 | 0.85 | FFAR1 (0.62) | FFAR1FFAR4EPHX2 | |
| Alcohol SCHEMBL28404120 | 0.84 | L3MBTL1 (0.52) | FFAR1ALDH1A1L3MBTL1ALOX5TDP1 | |
| SCHEMBL2773462 | 0.82 | FFAR1 (0.68) | FFAR1FFAR4NR1H4ALDH1A1LMNA | |
| SCHEMBL3744601 | 0.82 | FFAR1 (0.62) | FFAR1FFAR4NR1H4ALDH1A1LMNA | |
| SCHEMBL19825762 | 0.81 | FFAR1 (0.61) | FFAR1FFAR4NR1H4ALDH1A1LMNA | |
| SCHEMBL7059127 | 0.81 | PLAAT3 (0.61) | FFAR1FFAR4ALDH1A1L3MBTL1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098892-A | Angiotensin converting enzyme inhibitors as hypotensive agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| US-4822818-A | ANTIHYPERTENSIVE AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| US-4474692-A | L-Alanyl-N-(indan-2-yl)glycine, its esters and salts thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-10-02 | — | — | US | disclosed |
| EP-0051391-B1 | BICYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1984-09-05 | — | — | EP | disclosed |
| EP-0051391-A1 | Bicyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-05-12 | — | — | EP | disclosed |