Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335707 | 0.92 | L3MBTL1 (0.50) | POLBL3MBTL1MRGPRX4MAPTHTT | |
| SCHEMBL7332819 | 0.90 | L3MBTL1 (0.50) | POLBL3MBTL1ALDH1A1MRGPRX4MAPT | |
| SCHEMBL7328371 | 0.90 | L3MBTL1 (0.62) | POLBL3MBTL1ALDH1A1MRGPRX4KMT2A | |
| SCHEMBL7333993 | 0.89 | L3MBTL1 (0.51) | POLBL3MBTL1MRGPRX4MAPTKMT2A | |
| SCHEMBL7330976 | 0.87 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1MRGPRX4MAPTKMT2A | |
| SCHEMBL13225823 | 0.86 | MRGPRX4 (0.53) | POLBL3MBTL1ALDH1A1MRGPRX4MAPT | |
| SCHEMBL7330744 | 0.84 | L3MBTL1 (0.50) | POLBL3MBTL1MRGPRX4KMT2AHTT | |
| SCHEMBL7337342 | 0.82 | KMT2A (0.52) | POLBL3MBTL1MRGPRX4MAPTKMT2A | |
| SCHEMBL7328500 | 0.81 | POLB (0.56) | POLBL3MBTL1KMT2AMEN1ATM | |
| SCHEMBL7330946 | 0.79 | L3MBTL1 (0.52) | POLBL3MBTL1ALDH1A1MRGPRX4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430047-A | Neurotensin antagonists | WARNER-LAMBERT COMPANY (US) | 1995-07-04 | — | — | US | disclosed |