Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330946 | 0.90 | L3MBTL1 (0.52) | L3MBTL1POLBNPSR1HTTNPC1 | |
| SCHEMBL7330744 | 0.89 | L3MBTL1 (0.50) | L3MBTL1POLBNPSR1HTTNPC1 | |
| SCHEMBL7335707 | 0.89 | L3MBTL1 (0.50) | L3MBTL1POLBNPSR1HTTNPC1 | |
| SCHEMBL7336104 | 0.89 | POLB (0.52) | L3MBTL1POLBNPSR1HTTLMNA | |
| SCHEMBL13225823 | 0.87 | MRGPRX4 (0.53) | L3MBTL1POLBNPSR1HTTNPC1 | |
| SCHEMBL7328371 | 0.85 | L3MBTL1 (0.62) | L3MBTL1POLBNPSR1HTTNPC1 | |
| SCHEMBL7337342 | 0.85 | KMT2A (0.52) | L3MBTL1POLBMRGPRX4MEN1KMT2A | |
| SCHEMBL7328500 | 0.84 | POLB (0.56) | L3MBTL1POLBNPC1MEN1KMT2A | |
| SCHEMBL7330976 | 0.84 | L3MBTL1 (0.53) | L3MBTL1NPC1MRGPRX4MEN1KMT2A | |
| SCHEMBL7330045 | 0.82 | KMT2A (0.47) | POLBMRGPRX4MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430047-A | Neurotensin antagonists | WARNER-LAMBERT COMPANY (US) | 1995-07-04 | — | — | US | claimed |
| US-5430047-A | Neurotensin antagonists | WARNER-LAMBERT COMPANY (US) | 1995-07-04 | — | — | US | disclosed |