Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.31 |
| ▸ | CTSE | P14091 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.31 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.31 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.31 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.31 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.31 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.31 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.31 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.31 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.31 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | LONP1 | P36776 | 1/20 | 0.31 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.31 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.31 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28101256 | 0.85 | ANPEP (0.33) | AAK1 | |
| SCHEMBL3750901 | 0.78 | ANPEP (0.31) | — | |
| SCHEMBL7163147 | 0.77 | BACE1 (0.42) | CTSDBACE1 | |
| SCHEMBL7163139 | 0.77 | BACE1 (0.42) | CTSDBACE1 | |
| SCHEMBL28101251 | 0.75 | BACE1 (0.42) | CTSDBACE1 | |
| SCHEMBL29532207 | 0.74 | MME (0.41) | — | |
| SCHEMBL5598780 | 0.74 | CPB2 (0.34) | — | |
| SCHEMBL9561398 | 0.74 | ANPEP (0.31) | — | |
| SCHEMBL5526723 | 0.74 | OPRM1 (0.42) | CTSDBACE1 | |
| SCHEMBL4935995 | 0.74 | OPRM1 (0.42) | CTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298621-A | Peptides endcapped with purine derivative | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1994-03-29 | — | — | US | disclosed |
| US-5298621-A | Peptides endcapped with purine derivative | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1994-03-29 | — | — | US | disclosed |
| EP-0464009-A2 | Oligopeptide derivatives of ipoxantine endowed with immunomodulating activity and pharmaceutical compositions containing same | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1992-01-02 | — | — | EP | disclosed |
| EP-0464009-A2 | Oligopeptide derivatives of ipoxantine endowed with immunomodulating activity and pharmaceutical compositions containing same | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1992-01-02 | — | — | EP | disclosed |