Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | GPR6 | P46095 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12325748 | 0.78 | SIGMAR1 (0.76) | SIGMAR1ALDH1A1TSHRHTR1AHSD17B10 | |
| SCHEMBL7295692 | 0.78 | SIGMAR1 (1.00) | SIGMAR1ALDH1A1TSHRHTR1AHSD17B10 | |
| SCHEMBL12325717 | 0.78 | SIGMAR1 (0.76) | SIGMAR1ALDH1A1TSHRHTR1AHSD17B10 | |
| SCHEMBL12325670 | 0.78 | SIGMAR1 (0.75) | SIGMAR1ALDH1A1TSHRHTR1AHSD17B10 | |
| SCHEMBL8946200 | 0.76 | SIGMAR1 (0.65) | SIGMAR1ALDH1A1TSHRHTR1AMAPT | |
| SCHEMBL1387431 | 0.75 | ALDH1A1 (0.62) | SIGMAR1ALDH1A1TSHRHTR1AMAPT | |
| SCHEMBL7304070 | 0.74 | SIGMAR1 (0.70) | SIGMAR1ALDH1A1TSHRHTR1AHSD17B10 | |
| SCHEMBL12325719 | 0.74 | SIGMAR1 (0.69) | SIGMAR1ALDH1A1TSHRHTR1AHSD17B10 | |
| SCHEMBL7305251 | 0.74 | SIGMAR1 (0.76) | SIGMAR1ALDH1A1TSHRHTR1AHSD17B10 | |
| SCHEMBL1387341 | 0.73 | MAPT (0.57) | ALDH1A1TSHRHSD17B10MAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519023-A | SCHIZOPHRENIA | ADIR ET COMPAGNIE (FR) | 1996-05-21 | — | — | US | disclosed |
| EP-0580503-B1 | Aminoalkylchromones, process for their preparation and compositions containing them | ADIR (FR) | 1995-06-14 | — | — | EP | disclosed |
| EP-0580503-A1 | Aminoalkylchromones, process for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-01-26 | — | — | EP | disclosed |