Sugi Predict

Sugi Predict / Compounds / SCHEMBL73325

SCHEMBL73325

SCHEMBL73325

Nc1c(C(=O)N[C@@H](CC(=O)O)C(=O)O)ncn1[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ATIC P31939 2/20 0.69
▸ FBP1 P09467 2/20 0.69
▸ DNPH1 O43598 3/20 0.52
▸ TAS1R3 Q7RTX0 3/20 0.52
▸ TAS1R1 Q7RTX1 3/20 0.52
▸ PRKAB2 O43741 1/20 0.52
▸ TRPM2 O94759 1/20 0.52
▸ LDHA P00338 1/20 0.52
▸ ADRB2 P07550 1/20 0.52
▸ SRC P12931 1/20 0.52
▸ ADORA1 P30542 1/20 0.52
▸ P2RY2 P41231 1/20 0.52
▸ P2RY1 P47900 1/20 0.52
▸ PRKAG1 P54619 1/20 0.52
▸ PRKAA2 P54646 1/20 0.52
▸ PDE4D Q08499 1/20 0.52
▸ KCNH2 Q12809 1/20 0.52
▸ PRKAA1 Q13131 1/20 0.52
▸ PDE3A Q14432 1/20 0.52
▸ SMN1; SMN2 Q16637 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25738494 1.00 ATIC (0.69) ATICFBP1DNPH1TAS1R3TAS1R1
SCHEMBL28657318 1.00 ATIC (0.69) ATICFBP1DNPH1TAS1R3TAS1R1
SCHEMBL73326 1.00 ATIC (0.69) ATICFBP1DNPH1TAS1R3TAS1R1
SCHEMBL28657321 1.00 ATIC (0.69) ATICFBP1DNPH1TAS1R3TAS1R1
SCHEMBL19859098 1.00 ATIC (0.69) ATICFBP1DNPH1TAS1R3TAS1R1
SCHEMBL2509888 1.00 ATIC (0.69) ATICFBP1DNPH1TAS1R3TAS1R1
SCHEMBL21110493 1.00 ATIC (0.69) ATICFBP1DNPH1TAS1R3TAS1R1
SCHEMBL22567113 1.00 ATIC (0.69) ATICFBP1DNPH1TAS1R3TAS1R1
SCHEMBL22459604 1.00 ATIC (0.69) ATICFBP1DNPH1TAS1R3TAS1R1
SCHEMBL25738489 0.93 ATIC (0.67) ATICFBP1DNPH1TAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 539 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313852-A1 BIDIRECTIONAL CHEF1 VECTORS AGC BIOLOGICS INC (US) 2025-10-09 — — US claimed
CN-119074740-A Application of compound SAICAR in preparation of product for promoting wound healing 上海交通大学医学院附属第九人民医院 2024-12-06 — — CN claimed
CN-119074739-A Use of compound SAICAR in the preparation of a product for improving skin ageing 上海交通大学医学院附属第九人民医院 2024-12-06 — — CN claimed
CN-113603721-B Method for synthesizing SAICAR 重庆文理学院 2023-12-01 — — CN claimed
US-11684593-B2 Applications of spermine and its derivative in preparation of antitumor drug GENEHEAL BIOTECHNOLOGY CO., LTD. (CN) 2023-06-27 — — US claimed
EP-4158010-A1 METHODS FOR STABLE GENOMIC INTEGRATION IN RECOMBINANT MICROORGANISMS BioPlx, Inc. (US) 2023-04-05 — — EP claimed
CN-110678452-B Application of spermidine and derivatives thereof 广州君赫生物科技有限公司 2023-02-28 — — CN claimed
US-11517541-B2 Applications of spermidine and its derivatives GENEHEAL BIOTECHNOLOGY CO., LTD. (CN) 2022-12-06 — — US claimed
CN-110494131-B Application of spermine and derivatives thereof in preparation of antitumor drugs 广州君赫生物科技有限公司 2022-11-08 — — CN claimed
EP-3996510-A2 LIVE BIOTHERAPEUTIC COMPOSITIONS AND METHODS BioPlx, Inc. (US) 2022-05-18 — — EP claimed
WO-2011139914-A1 METABOLIC BIOMARKERS OF AUTISM WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2011-11-10 — — WO claimed
WO-2011017606-A1 METHODS FOR IMPROVING RECOMBINANT PROTEIN EXPRESSION CMC ICOS BIOLOGICS, INC. (US) 2011-02-10 — — WO claimed
US-20100323979-A1 METHODS AND COMPOSITIONS FOR INHIBITING PROLIFERATION OF ANEUPLOID CELLS MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2010-12-23 — — US claimed
WO-2010147663-A1 METHODS AND COMPOSITIONS FOR INHIBITING PROLIFERATION OF ANEUPLOID CELLS MASSECHUSETTS INSTITUTE OF TECHNOLOGY (US) 2010-12-23 — — WO claimed
WO-2009128644-A9 GENOME-SCALE BUTANOL-PRODUCING MICROORGANISM METABOLIC NETWORK MODEL AND METHODS USING THE SAME FOR ANALYSIS OF METABOLIC CHARACTERISTICS OF BUTANOL-PRODUCING MICROORGANISMS AND FOR SCREENING DELETION TARGETS 한국과학기술원 (KR) 2010-04-15 — — WO claimed
WO-2009128644-A2 GENOME-SCALE BUTANOL-PRODUCING MICROORGANISM METABOLIC NETWORK MODEL AND METHODS USING THE SAME FOR ANALYSIS OF METABOLIC CHARACTERISTICS OF BUTANOL-PRODUCING MICROORGANISMS AND FOR SCREENING DELETION TARGETS 한국과학기술원 (KR) 2009-10-22 — — WO claimed
US-20050002943-A1 Amp-kinase agonists or adenosine pro-drugs as immuno-stimulating agents UNIVERSITE LIBRE DE BRUXELLES (BE) 2005-01-06 — — US claimed
EP-1492564-A2 AMP-KINASE AGONISTS OR ADENOSINE PRO-DRUGS AS IMMUNO-STIMULATING AGENTS Université Libre de Bruxelles (BE) 2005-01-05 — — EP claimed
US-20030166201-A1 Selection systems for genetically modified cells CITY OF HOPE 2003-09-04 — — US claimed
WO-2003037371-A2 AMP-KINASE AGONISTS OR ADENOSINE PRO-DRUGS AS IMMUNO-STIMULATING AGENTS UNIVERSITE LIBRE DE BRUXELLES (BE) 2003-05-08 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11517541-B2 Applications of spermidine and its derivatives SRM, SMS, SMOX ATIC 568/4885FBP1 1923/4885DNPH1 2829/4885
US-11684593-B2 Applications of spermine and its derivative in preparation of antitumor drug SRM, SMS, SMOX ATIC 290/4885FBP1 284/4885DNPH1 1316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.