SCHEMBL733349

SCHEMBL733349

CC(=O)CCC(=S)ON1C(=O)CCC1=O

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.31
SLC15A2 Q16348 1/20 0.31
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28965160 0.90 PAOX (0.31)
SCHEMBL142707 0.84 MGAM (0.31) ALDH1A1GLA
SCHEMBL462606 0.81 ALDH1A1 (0.39) ALDH1A1LMNASLC15A2GLA
SCHEMBL10071372 0.75 SMN1; SMN2 (0.38) ALDH1A1
SCHEMBL829438 0.75 SMN1; SMN2 (0.35) ALDH1A1GLA
SCHEMBL28381750 0.75 PSMB8 (0.33) GLA
SCHEMBL4618888 0.74 GLA (0.32) GLA
SCHEMBL10071373 0.74 SMN1; SMN2 (0.40) ALDH1A1
SCHEMBL12896267 0.74 SMN1; SMN2 (0.40) ALDH1A1
SCHEMBL469600 0.74 SMN1; SMN2 (0.40) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4388014-A1 MULTIVALENT ANTI-VARIANT FC-REGION ANTIBODIES AND METHODS OF USE F. Hoffmann-La Roche AG (CH) 2024-06-26 EP claimed
CN-117858905-A Multivalent anti-variant FC region antibodies and methods of use 豪夫迈·罗氏有限公司 2024-04-09 CN claimed
WO-2023021055-A1 MULTIVALENT ANTI-VARIANT FC-REGION ANTIBODIES AND METHODS OF USE F. HOFFMANN-LA ROCHE AG (CH) 2023-02-23 WO claimed
WO-2010078376-A2 FC-SPECIFIC POLYMER-CONJUGATED ANTIBODIES AND THEIR DIAGNOSTIC USE VENTANA MEDICAL SYSTEMS, INC. (US) 2010-07-08 WO claimed
EP-0382781-B1 COMPOSITION FOR TREATING CANCERS CHARACTERIZED BY OVER-EXPRESSION OF THE C-FMS PROTO-ONCOGENE GENETICS INSTITUTE, INC. (US) 1993-09-29 EP claimed
US-20260109728-A1 IMMUNOMODULATING POLYNUCLEOTIDES, ANTIBODY CONJUGATES THEREOF, AND METHODS OF THEIR USE TALLAC THERAPEUTICS INC (US) 2026-04-23 US disclosed
US-12351598-B2 Immunomodulating polynucleotides, antibody conjugates thereof, and methods of their use Tallac Therapeutics, Inc. (US) 2025-07-08 US disclosed
US-12280021-B2 Affinity medicant conjugate AF CHEMICALS, LLC (US) 2025-04-22 US disclosed
EP-4257186-B1 AFFINITY MEDICANT CONJUGATES AF CHEMICALS LLC (US) 2024-12-04 EP disclosed
EP-4388014-A1 MULTIVALENT ANTI-VARIANT FC-REGION ANTIBODIES AND METHODS OF USE F. Hoffmann-La Roche AG (CH) 2024-06-26 EP disclosed
CN-117858905-A Multivalent anti-variant FC region antibodies and methods of use 豪夫迈·罗氏有限公司 2024-04-09 CN disclosed
US-20230372267-A1 AFFINITY MEDICANT CONJUGATE Califia Pharma Inc. (US) 2023-11-23 US disclosed
US-5998157-A CONTACTING SAMPLE WITH ANTIBODY AND BINDING PARTNER IN PRESENCE OF ACYLATED PROTEIN AGGREGATE ROCHE DIAGNOSTICS GMBH (DE) 1999-12-07 US disclosed
WO-1998056353-A1 INTERNALLY SUPPORTED LIPID VESICLE SYSTEMS MALIK NAVID (GB) 1998-12-17 WO disclosed
US-5658725-A REDUCING NON-SPECIFIC INTERACTIONS BOEHRINGER MANNHEIM GMBH (DE) 1997-08-19 US disclosed
EP-0685070-A1 ACYLATED PROTEIN AGGREGATES AND THEIR USE IN SUPPRESSING INTERFERENCE IN IMMUNOASSAYS Roche Diagnostics GmbH (DE) 1995-12-06 EP disclosed
EP-0684956-A1 ACYLATED PROTEIN AGGREGATES AND THEIR USE IN ENHANCING SIGNALS IN AN IMMUNOASSAY TESTING FOR ANTIBODIES Roche Diagnostics GmbH (DE) 1995-12-06 EP disclosed
WO-1995017668-A1 ACYLATED PROTEIN AGGREGATES AND THEIR USE IN SUPPRESSING INTERFERENCE IN IMMUNOASSAYS BOEHRINGER MANNHEIM GMBH (DE) 1995-06-29 WO disclosed
WO-1995017427-A1 ACYLATED PROTEIN AGGREGATES AND THEIR USE IN ENHANCING SIGNALS IN AN IMMUNOASSAY TESTING FOR ANTIBODIES BOEHRINGER MANNHEIM GMBH (DE) 1995-06-29 WO disclosed
EP-0382781-B1 COMPOSITION FOR TREATING CANCERS CHARACTERIZED BY OVER-EXPRESSION OF THE C-FMS PROTO-ONCOGENE GENETICS INSTITUTE, INC. (US) 1993-09-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12280021-B2 Affinity medicant conjugate FCER2, HDGF, FCGR2A ALDH1A1 3966/4885LMNA 3666/4885SLC15A2 2765/4885
US-20230372267-A1 AFFINITY MEDICANT CONJUGATE FCER2, HDGF, FCGR2A ALDH1A1 3966/4885LMNA 3666/4885SLC15A2 2765/4885
US-12351598-B2 Immunomodulating polynucleotides, antibody conjugates thereof, and methods of their use TYMP, DUT, PAICS ALDH1A1 2398/4885LMNA 3368/4885SLC15A2 3717/4885
US-20260109728-A1 IMMUNOMODULATING POLYNUCLEOTIDES, ANTIBODY CONJUGATES THEREOF, AND METHODS OF THEIR USE UNG, DUT, TYMP ALDH1A1 3842/4885LMNA 926/4885SLC15A2 1307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.