Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.49 |
| ▸ | MEN1 | O00255 | 10/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330798 | 0.85 | MAPT (0.56) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL7343524 | 0.84 | F11 (0.45) | ALDH1A1SMN1; SMN2RAB9AHTTHPGD | |
| SCHEMBL7341144 | 0.84 | IMPDH2 (0.44) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7338363 | 0.84 | ALDH1A1 (0.42) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL7339841 | 0.84 | ALDH1A1 (0.44) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7331572 | 0.84 | ALDH1A1 (0.47) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL7333593 | 0.83 | F11 (0.49) | POLB | |
| SCHEMBL7342249 | 0.83 | ADRB1 (0.47) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL7336287 | 0.82 | SMN1; SMN2 (0.43) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL7332390 | 0.81 | ALDH1A1 (0.47) | MAPTKMT2AMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475531-B1 | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same | ASAHI CHEMICAL IND (JP) | 1995-01-18 | — | — | EP | disclosed |
| EP-0475531-A1 | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-03-18 | — | — | EP | disclosed |