Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.32 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL733399 | 0.77 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10FAAHSMN1; SMN2 | |
| SCHEMBL732430 | 0.71 | — | — | |
| SCHEMBL10530238 | 0.66 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10FAAHSMN1; SMN2 | |
| SCHEMBL311876 | 0.66 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10FAAHSMN1; SMN2 | |
| SCHEMBL10458150 | 0.66 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10FAAHSMN1; SMN2 | |
| SCHEMBL10530231 | 0.66 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10FAAHSMN1; SMN2 | |
| SCHEMBL4869307 | 0.66 | — | — | |
| SCHEMBL4688208 | 0.66 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10FAAHSMN1; SMN2 | |
| SCHEMBL36403 | 0.66 | — | — | |
| SCHEMBL27822761 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138118-B2 | Plant safening agents ; side effect reduction of pesticides, herbicides, insecticides, fungicides | BAYER CROPSCIENCE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-7838463-B2 | Safeners based on acrylic-aliphatic carboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2010-11-23 | — | — | US | disclosed |
| EP-1653804-A1 | USE OF AROMATIC COMPOUNDS AS SAFENERS | Bayer CropScience GmbH (DE) | 2006-05-10 | — | — | EP | disclosed |
| EP-1653806-A1 | SAFENER BASED ON AROMATIC-ALIPHATIC CARBOXYLIC ACID DERIVATIVES | Bayer CropScience GmbH (DE) | 2006-05-10 | — | — | EP | disclosed |
| EP-1610611-A1 | USE OF AROMATIC HYDROXY COMPOUNDS AS SAFENERS | Bayer CropScience GmbH (DE) | 2006-01-04 | — | — | EP | disclosed |
| US-20050049145-A1 | Safeners based on acrylic-aliphatic carboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2005-03-03 | — | — | US | disclosed |
| WO-2005016001-A1 | SAFENER BASED ON AROMATIC-ALIPHATIC CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE GMBH (DE) | 2005-02-24 | — | — | WO | disclosed |
| WO-2005015994-A1 | USE OF AROMATIC COMPOUNDS AS SAFENERS | BAYER CROPSCIENCE GMBH (DE) | 2005-02-24 | — | — | WO | disclosed |
| US-20050037922-A1 | Use of hydroxyaromatics as safeners | BAYER CROPSCIENCE GMBH (DE) | 2005-02-17 | — | — | US | disclosed |
| US-20040224844-A1 | Use of hydroxyaromatic compounds as safeners | BAYER CROPSCIENCE GMBH (DE) | 2004-11-11 | — | — | US | disclosed |
| WO-2004084631-A1 | USE OF AROMATIC HYDROXY COMPOUNDS AS SAFENERS | BAYER CROPSCIENCE GMBH (DE) | 2004-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050037922-A1 | Use of hydroxyaromatics as safeners | CBR1, CYP8B1, AHR | ALDH1A1 486/4885LMNA 2857/4885HSD17B10 143/4885 |
| US-20050049145-A1 | Safeners based on acrylic-aliphatic carboxylic acid derivatives | GRHPR, HCAR1, HCAR3 | ALDH1A1 670/4885LMNA 2990/4885HSD17B10 241/4885 |
| US-20040224844-A1 | Use of hydroxyaromatic compounds as safeners | CBR1, CYC1, NR2E1 | ALDH1A1 1462/4885LMNA 3966/4885HSD17B10 265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.