Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306429 | 0.97 | LIPG (0.34) | LIPGFOXM1NPC1 | |
| SCHEMBL7294572 | 0.95 | NPC1 (0.36) | LIPGFOXM1NPC1 | |
| SCHEMBL7306535 | 0.93 | LIPG (0.35) | LIPG | |
| SCHEMBL7304360 | 0.85 | FFAR4 (0.33) | — | |
| SCHEMBL1712015 | 0.84 | CTSL (0.39) | — | |
| SCHEMBL7327424 | 0.84 | MEN1 (0.38) | — | |
| SCHEMBL21456425 | 0.83 | TSHR (0.48) | LIPGLTA4HFOXM1 | |
| SCHEMBL7295050 | 0.82 | FFAR4 (0.33) | FOXM1NPC1 | |
| SCHEMBL20129240 | 0.81 | TSHR (0.47) | LIPGLTA4HFOXM1 | |
| SCHEMBL20129162 | 0.81 | TSHR (0.47) | LIPGLTA4HFOXM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135932-A | 2-HYDROXYPROPYLAMINO-ALKYL-BENZIMIDAZOLY-5-YL DERIVATIVES AND THEIR USE IN THE TREATMENT OF HEART DISEASE | DR. KARL THOMAE GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0400519-A1 | 2-Hydroxy-n-propylamines, medicaments containing these compounds and method for preparing them | Dr. Karl Thomae GmbH (DE) | 1990-12-05 | — | — | EP | disclosed |