Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 10/20 | 0.37 |
| ▸ | GAA | P10253 | 8/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.37 |
| ▸ | CASP1 | P29466 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 4/20 | 0.37 |
| ▸ | CASP7 | P55210 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594709 | 0.76 | KDM4E (0.41) | KDM4EALDH1A1RCE1ADORA3ADORA2A | |
| SCHEMBL4044550 | 0.66 | ADORA2A (0.62) | KDM4EALDH1A1ADORA3ADORA2AADORA2B | |
| SCHEMBL5653328 | 0.62 | ADORA2A (0.46) | KDM4EALDH1A1RCE1ADORA3ADORA2A | |
| SCHEMBL9834157 | 0.62 | TSHR (0.41) | KDM4EALDH1A1RCE1ADORA3ADORA2A | |
| SCHEMBL7346473 | 0.60 | MEN1 (0.35) | ALDH1A1MEN1KMT2A | |
| SCHEMBL23846017 | 0.58 | LMNA (0.46) | KDM4EALDH1A1ADORA3ADORA2AADORA2B | |
| SCHEMBL30507669 | 0.58 | LMNA (0.46) | KDM4EALDH1A1ADORA3ADORA2AADORA2B | |
| SCHEMBL25919980 | 0.58 | ADORA2A (0.42) | KDM4EALDH1A1RCE1ADORA3ADORA2A | |
| SCHEMBL5103140 | 0.56 | KDM4E (0.51) | KDM4EALDH1A1RCE1ADORA3ADORA2A | |
| SCHEMBL23828527 | 0.56 | ALDH1A1 (0.47) | KDM4EALDH1A1RCE1ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995001356-A1 | 1,2,4-TRIAZOLO[1,5-c]PYRIMIDINE HETEROCYCLIC ANALOGUES HAVING ANTAGONISTIC ACTIVITY ON ADENOSINE A2 RECEPTOR | SCHERING-PLOUGH S.P.A. (IT) | 1995-01-12 | — | — | WO | disclosed |