Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335239 | 0.84 | CTSK (0.41) | CTSK | |
| SCHEMBL8992436 | 0.74 | NPSR1 (0.43) | CTSKALDH1A1ATMTDP1LMNA | |
| SCHEMBL7272919 | 0.73 | CPB2 (0.50) | CTSKCTSS | |
| SCHEMBL7400373 | 0.73 | CTSS (0.36) | CTSKCTSSATMTDP1 | |
| SCHEMBL2425411 | 0.73 | CTSS (0.36) | CTSKCTSSATMTDP1 | |
| SCHEMBL7271490 | 0.70 | ITGB3 (0.53) | — | |
| SCHEMBL10697416 | 0.70 | KCNH2 (0.50) | ALDH1A1 | |
| SCHEMBL9817100 | 0.70 | KCNH2 (0.50) | ALDH1A1 | |
| SCHEMBL730079 | 0.70 | KCNH2 (0.50) | ALDH1A1 | |
| SCHEMBL4445935 | 0.70 | KCNH2 (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486011-A2 | Pharmaceutical composition against Pneumocystis carinii | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-05-20 | — | — | EP | disclosed |