SCHEMBL7335286

SCHEMBL7335286

CC(C)C[C@H](NC(=O)OC(C)[Si](C)(C)C)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 10/20 0.57
ALDH1A1 P00352 2/20 0.53
MEN1 O00255 1/20 0.50
LMNA P02545 1/20 0.50
KMT2A Q03164 1/20 0.50
MAPT P10636 1/20 0.47
LAP3 P28838 3/20 0.46
TYR P14679 1/20 0.43
PLA2G2A P14555 2/20 0.41
PLA2G5 P39877 2/20 0.41
GRN P28799 1/20 0.41
SORT1 Q99523 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7329855 0.85 FOLH1 (0.45) FOLH1ALDH1A1MEN1LMNAKMT2A
SCHEMBL7328619 0.85 TAS1R3 (0.46) FOLH1
SCHEMBL9162661 0.85 TGFBR1 (0.47) FOLH1ALDH1A1
SCHEMBL23964665 0.82 FOLH1 (0.64) FOLH1ALDH1A1MEN1LMNAKMT2A
SCHEMBL27337953 0.82 FOLH1 (0.64) FOLH1ALDH1A1MEN1LMNAKMT2A
SCHEMBL628966 0.78 ALDH1A1 (0.64) FOLH1ALDH1A1MEN1LMNAKMT2A
SCHEMBL628967 0.78 ALDH1A1 (0.64) FOLH1ALDH1A1MEN1LMNAKMT2A
SCHEMBL3447885 0.78 ALDH1A1 (0.64) FOLH1ALDH1A1MEN1LMNAKMT2A
SCHEMBL23964781 0.78 FOLH1 (0.59) FOLH1ALDH1A1MEN1LMNAKMT2A
SCHEMBL10460259 0.76 MME (0.50) LMNAKMT2ATYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0393457-B1 Proteinase inhibitor SUNTORY LTD (JP) 1994-07-06 EP disclosed