SCHEMBL7328619

SCHEMBL7328619

COC(=O)[C@H](CC(C)C)NC(=O)OC(C)[Si](C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 10/20 0.46
TAS1R1 Q7RTX1 10/20 0.46
BIRC2 Q13490 1/20 0.43
POLB P06746 1/20 0.43
FOLH1 Q04609 5/20 0.43
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7335286 0.85 FOLH1 (0.57) FOLH1
SCHEMBL7327842 0.83 BIRC2 (0.46) TAS1R3TAS1R1BIRC2FOLH1
SCHEMBL7751184 0.81 TAS1R3 (0.54) TAS1R3TAS1R1BIRC2POLBFOLH1
SCHEMBL11434953 0.81 TAS1R3 (0.54) TAS1R3TAS1R1BIRC2POLBFOLH1
SCHEMBL7328622 0.77 TAS1R3 (0.46) TAS1R3TAS1R1BIRC2POLBFOLH1
SCHEMBL55833 0.73 CTSL (0.60) TAS1R3TAS1R1BIRC2POLBFOLH1
SCHEMBL56907 0.73 CTSL (0.60) TAS1R3TAS1R1BIRC2POLBFOLH1
SCHEMBL9162661 0.73 TGFBR1 (0.47) FOLH1
SCHEMBL55832 0.73 CTSL (0.60) TAS1R3TAS1R1BIRC2POLBFOLH1
SCHEMBL23616324 0.73 TAS1R3 (0.58) TAS1R3TAS1R1BIRC2POLBFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0393457-B1 Proteinase inhibitor SUNTORY LTD (JP) 1994-07-06 EP disclosed
EP-0393457-A1 Proteinase inhibitor SUNTORY LIMITED (JP) 1990-10-24 EP disclosed