SCHEMBL7335291

SCHEMBL7335291

CCCCCC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C=O)CCCC

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CTSK P43235 7/20 0.53
PLA2G10 O15496 2/20 0.50
MEN1 O00255 1/20 0.45
FAAH O00519 1/20 0.45
MAPK1 P28482 1/20 0.45
KMT2A Q03164 1/20 0.45
PSMB5 P28074 4/20 0.45
NOD1 Q9Y239 2/20 0.45
PLA2G2A P14555 2/20 0.43
PLA2G5 P39877 2/20 0.43
PLA2G2C Q5R387 1/20 0.42
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7379299 0.99 CTSK (0.52) CTSKPLA2G10MEN1FAAHMAPK1
SCHEMBL7335399 0.99 CTSK (0.52) CTSKPLA2G10MEN1FAAHMAPK1
SCHEMBL7327504 0.88 CTSK (0.54) CTSKPLA2G10PSMB5CTSLCTSB
SCHEMBL11142020 0.86 NPY4R (0.54) CTSKPLA2G10NOD1
SCHEMBL5712420 0.85 CTSK (0.57) CTSKPLA2G2APLA2G5CTSLCTSB
SCHEMBL8972183 0.85 CTSK (0.57) CTSKCTSLCTSB
SCHEMBL8695376 0.85 CTSK (0.57) CTSKCTSLCTSB
SCHEMBL8387889 0.85 CTSK (0.57) CTSKCTSLCTSB
Hydrochloric Acid SCHEMBL11137889 0.85 NPY4R (0.54) PLA2G10NOD1
SCHEMBL9642155 0.84 CTSK (0.59) CTSKPSMB5CTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5510531-A ANTIINFLAMMATROY AGENTS, MUSCULAR DISORDERS SUNTORY LIMITED (JP) 1996-04-23 US disclosed
EP-0393457-B1 Proteinase inhibitor SUNTORY LTD (JP) 1994-07-06 EP disclosed
US-5081284-A N-Oxomethyl-Substituted Peptide SUNTORY LIMITED (JP) 1992-01-14 US disclosed
EP-0393457-A1 Proteinase inhibitor SUNTORY LIMITED (JP) 1990-10-24 EP disclosed