Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7289243 | 0.70 | GAA (0.56) | GAAKDM4EATMPDE4APDE4B | |
| SCHEMBL7335311 | 0.69 | GAA (0.46) | GAAKDM4EATMPDE4APDE4B | |
| SCHEMBL7282267 | 0.67 | GAA (0.41) | GAAKDM4EATMPDE4APDE4B | |
| SCHEMBL7288660 | 0.66 | PDE4A (0.38) | GAAKDM4EATMPDE4APDE4B | |
| SCHEMBL21048253 | 0.61 | GAA (0.41) | GAAKDM4EATMALDH1A1 | |
| SCHEMBL10466353 | 0.60 | GAA (1.00) | GAAKDM4EATMPDE4APDE4B | |
| SCHEMBL27389569 | 0.59 | GAA (0.54) | GAAKDM4EATMPDE4APDE4B | |
| SCHEMBL3797196 | 0.55 | KDM4E (0.68) | GAAKDM4EATMUPP1ALDH1A1 | |
| SCHEMBL172129 | 0.55 | ALDH1A1 (0.37) | GAAKDM4EALDH1A1 | |
| SCHEMBL29958173 | 0.54 | KDM4E (0.37) | GAAKDM4EATMUPP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002949-A | Anticoagulants | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |