Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718209 | 0.75 | XDH (0.39) | ALDH1A1L3MBTL1MAPT | |
| SCHEMBL9408132 | 0.66 | MEN1 (0.51) | ALDH1A1MAPK1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL14129814 | 0.66 | L3MBTL1 (0.44) | ALDH1A1L3MBTL1SMN1; SMN2GAAKDM4E | |
| SCHEMBL8312414 | 0.65 | — | — | |
| SCHEMBL12102045 | 0.64 | MAPK1 (0.55) | ALDH1A1L3MBTL1MAPK1SMN1; SMN2ADORA3 | |
| SCHEMBL172127 | 0.63 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MAPK1PARP1SMN1; SMN2 | |
| Water SCHEMBL7594637 | 0.63 | — | — | |
| Iodide SCHEMBL3791320 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL9663276 | 0.63 | — | — | |
| SCHEMBL1439539 | 0.62 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1PARP1ADORA3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381177-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | TES PHARMA S.R.L. (IT) | 2023-11-30 | — | — | US | disclosed |
| WO-2020239107-A1 | TETRACYCLIC COMPOUNDS AS CDC7 INHIBITORS | 正大天晴药业集团股份有限公司 | 2020-12-03 | — | — | WO | disclosed |
| US-9708272-B2 | Inhibitors of α-amino-β-carboxymuconic acid semialdehyde decarboxylase | TES PHARMA S.R.L. (IT) | 2017-07-18 | — | — | US | disclosed |
| US-20160060226-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | TES PHARMA S.R.L. (IT) | 2016-03-03 | — | — | US | disclosed |
| EP-2213674-B1 | PURIFICATION METHOD OF PEMETREXED SALTS,SODIUM SALTS AND DISODIUM SALTS | CHONGQING PHARM RES INST CO (CN) | 2012-03-07 | — | — | EP | disclosed |
| US-20100305319-A1 | METHOD OF PURIFYING A SALT, SODIUM SALT AND DISODIUM SALT OF PEMETREXED | Chongquing Pharmaceutical Research Institute Co. ltd (CN) | 2010-12-02 | — | — | US | disclosed |
| US-20100305319-A1 | METHOD OF PURIFYING A SALT, SODIUM SALT AND DISODIUM SALT OF PEMETREXED | Chongquing Pharmaceutical Research Institute Co. ltd (CN) | 2010-12-02 | — | — | US | disclosed |
| EP-2213674-A1 | PURIFICATION METHOD OF PEMETREXED SALTS,SODIUM SALTS AND DISODIUM SALTS | Chongqing Pharmaceutical Research Institute Co., Ltd. (CN) | 2010-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160060226-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | ACMSD, GLS, ALDH7A1 | ALDH1A1 171/4885L3MBTL1 2418/4885MAPK1 3141/4885 |
| US-20100305319-A1 | METHOD OF PURIFYING A SALT, SODIUM SALT AND DISODIUM SALT OF PEMETREXED | SLC13A3, SLC34A3, SLC28A1 | ALDH1A1 2625/4885L3MBTL1 2850/4885MAPK1 779/4885 |
| US-20230381177-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | ACMSD, GLS, ALDH7A1 | ALDH1A1 171/4885L3MBTL1 2418/4885MAPK1 3141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.