Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.34 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7335067 | 0.87 | ASIC3 (0.46) | PLAUFFAR1ASIC3 | |
| SCHEMBL7340246 | 0.82 | MMP13 (0.38) | PLAUFFAR1ASIC3 | |
| SCHEMBL7337629 | 0.82 | CXCR2 (0.41) | PLAUFFAR1ASIC3 | |
| SCHEMBL7342370 | 0.81 | PLAU (0.46) | PLAU | |
| SCHEMBL7337820 | 0.80 | HAO1 (0.32) | — | |
| SCHEMBL7337460 | 0.79 | PLAU (0.32) | PLAU | |
| SCHEMBL7336015 | 0.78 | PLAU (0.34) | PLAU | |
| SCHEMBL7338537 | 0.78 | ITGB3 (0.36) | — | |
| SCHEMBL7337502 | 0.78 | NPC1 (0.43) | PLAU | |
| Trifluoroacetic Acid SCHEMBL7335751 | 0.74 | PLAU (0.80) | PLAUFFAR1ASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010049374-A1 | Urokinase inhibitors | STEELE ANDREW W (US) | 2001-12-06 | — | — | US | disclosed |
| US-6284796-B1 | NAPHTHAMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | disclosed |
| US-6258822-B1 | ENZYME INHIBITORS OF NAPHTHALENE AMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-07-10 | — | — | US | disclosed |
| EP-1000018-A2 | UROKINASE INHIBITORS | Abbott Laboratories (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999005096-A2 | UROKINASE INHIBITORS | ABBOTT LABORATORIES (US) | 1999-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010049374-A1 | Urokinase inhibitors | SERPINE1, PLAU, SERPINB1 | PLAU 2/4885FFAR1 2198/4885ASIC3 4314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.