Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.50 |
| ▸ | TMPRSS15 | P98073 | 6/20 | 0.50 |
| ▸ | MDM4 | O15151 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326757 | 0.89 | ITGB3 (0.51) | ITGB3ITGA2BPRSS1TMPRSS15MDM4 | |
| SCHEMBL7303302 | 0.84 | ITGB3 (0.66) | ITGB3ITGA2BPRSS1TMPRSS15ST14 | |
| SCHEMBL9272405 | 0.84 | ITGB3 (0.66) | ITGB3ITGA2BPRSS1TMPRSS15ST14 | |
| Hydrochloric Acid SCHEMBL8885572 | 0.81 | ITGB3 (0.56) | ITGB3ITGA2BPRSS1TMPRSS15MDM4 | |
| SCHEMBL7436661 | 0.80 | ITGB3 (0.74) | ITGB3ITGA2BPRSS1TMPRSS15ST14 | |
| SCHEMBL9224285 | 0.80 | CASP1 (0.47) | ITGB3ITGA2B | |
| SCHEMBL7431042 | 0.78 | ITGB3 (0.70) | ITGB3ITGA2BPRSS1TMPRSS15ST14 | |
| Hydrochloric Acid SCHEMBL8886078 | 0.76 | ITGB3 (0.59) | ITGB3ITGA2BPRSS1TMPRSS15ST14 | |
| SCHEMBL7332549 | 0.76 | FOLH1 (0.49) | ITGB3ITGA2BPRSS1TMPRSS15 | |
| SCHEMBL7333071 | 0.76 | MEN1 (0.43) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445796-B1 | Derivatives of acetic acid containing peptide bonds | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | EP | claimed |
| EP-0445796-A2 | Derivatives of acetic acid | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-11 | — | — | EP | claimed |
| EP-0445796-B1 | Derivatives of acetic acid containing peptide bonds | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | EP | disclosed |
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5273982-A | An amidinoaryleneamidoalkylpiperazinyleneacetic acid | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |
| EP-0445796-A2 | Derivatives of acetic acid | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-11 | — | — | EP | disclosed |