Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.82 |
| ▸ | POLB | P06746 | 2/20 | 0.82 |
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | CA2 | P00918 | 5/20 | 0.69 |
| ▸ | CA12 | O43570 | 3/20 | 0.69 |
| ▸ | CA9 | Q16790 | 3/20 | 0.69 |
| ▸ | CA3 | P07451 | 2/20 | 0.69 |
| ▸ | CA5A | P35218 | 2/20 | 0.69 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.69 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.69 |
| ▸ | CA4 | P22748 | 1/20 | 0.69 |
| ▸ | CA6 | P23280 | 1/20 | 0.69 |
| ▸ | CA7 | P43166 | 1/20 | 0.69 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3221326 | 0.98 | MEN1 (0.83) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL712856 | 0.98 | MEN1 (0.83) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL3215133 | 0.98 | MEN1 (0.83) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL16210325 | 0.98 | MEN1 (0.83) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL2994990 | 0.98 | MEN1 (0.83) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL865618 | 0.93 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL27889238 | 0.91 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL29982917 | 0.88 | MEN1 (1.00) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL27056159 | 0.87 | MEN1 (0.66) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL733643 | 0.83 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4572795-A2 | METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-BINDING ADJUVANTS | The University of Chicago (US) | 2025-06-25 | — | — | EP | disclosed |
| US-20250122502-A1 | Bifunctional Molecules and Methods of Using Thereof | FLAGSHIP PIONEERING, INC. (US) | 2025-04-17 | — | — | US | disclosed |
| US-20250114441-A1 | POLYMERIC VACCINE FOR OPIOID ADDICTION | THE JOHNS HOPKINS UNVERSITY | 2025-04-10 | — | — | US | disclosed |
| US-20240400684-A1 | ANTIBODY-MEDIATED DELIVERY OF CAS9 TO MAMMALIAN CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-12-05 | — | — | US | disclosed |
| WO-2024040169-A2 | METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-BINDING ADJUVANTS | THE UNIVERSITY OF CHICAGO (US) | 2024-02-22 | — | — | WO | disclosed |
| US-20230332145-A1 | BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF | FLAGSHIP PIONEERING, INC. (US) | 2023-10-19 | — | — | US | disclosed |
| WO-2023174773-A1 | PHOTOALIGNING MATERIALS | Rolic Technologies AG (CH) | 2023-09-21 | — | — | WO | disclosed |
| US-20230167450-A1 | BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF | FLAGSHIP PIONEERING, INC. (US) | 2023-06-01 | — | — | US | disclosed |
| US-20230158156-A1 | BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF | FLAGSHIP PIONEERING, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| WO-2023049816-A9 | BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF | FLAGSHIP PIONEERING, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| US-6552015-B2 | Inhibition of serotonin reuptake; especially 2-(azabicycloalkyl)alkylenyl)isoquinolin-3-one compounds | PFIZER INC. | 2003-04-22 | — | — | US | disclosed |
| US-20020052355-A1 | Azabicycloalkane derivatives and therapeutic uses thereof | PFIZER PRODUCTS INC. | 2002-05-02 | — | — | US | disclosed |
| EP-1178048-A1 | Azabicycloalkane derivatives for use as serotonin reuptake inhibitors and 5HT2a antagonists | Pfizer Products Inc. (US) | 2002-02-06 | — | — | EP | disclosed |
| US-6197963-B1 | TETRAHYDROPYRAN DERIVATIVES; PROTEIN G, SOMATOSTATIN, AND NATURAL KILLER CELL RECEPTOR ANTAGONISTS OR MIMETICS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2001-03-06 | — | — | US | disclosed |
| US-5811512-A | BINDING TO G-PROTEIN-LINKED RECEPTORS, SUBSTANCE P RECEPTOR; HORMONE INHIBITORS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1998-09-22 | — | — | US | disclosed |
| EP-0728007-A4 | NON-PEPTIDE PEPTIDOMIMETICS | UNIV PENNSYLVANIA (US) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997028172-A1 | NON-PEPTIDE PEPTIDOMIMETICS AND RELATED CYCLIC HEXAPEPTIDES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1997-08-07 | — | — | WO | disclosed |
| US-5552534-A | COMPOUNDS FOR CROSS REACTION WITH PEPTIDES FOR BINDING G PROTEIN | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1996-09-03 | — | — | US | disclosed |
| EP-0728007-A1 | NON-PEPTIDE PEPTIDOMIMETICS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995011686-A1 | NON-PEPTIDE PEPTIDOMIMETICS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1995-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158156-A1 | BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF | EFTUD2, SNRPE, DDX21 | ALDH1A1 4193/4885SMN1; SMN2 2320/4885POLB 361/4885 |
| US-20250114441-A1 | POLYMERIC VACCINE FOR OPIOID ADDICTION | OPRM1, OPRK1, OPRL1 | ALDH1A1 2483/4885SMN1; SMN2 2039/4885POLB 3216/4885 |
| US-20020052355-A1 | Azabicycloalkane derivatives and therapeutic uses thereof | HTR5A, HTR1A, HTR2A | ALDH1A1 449/4885SMN1; SMN2 2210/4885POLB 3583/4885 |
| US-20230332145-A1 | BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF | EFTUD2, DDX21, SNRPE | ALDH1A1 4159/4885SMN1; SMN2 2703/4885POLB 526/4885 |
| US-20250122502-A1 | Bifunctional Molecules and Methods of Using Thereof | EFTUD2, DDX21, SNRPE | ALDH1A1 4159/4885SMN1; SMN2 2703/4885POLB 526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.