Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4697134 | 0.91 | ALDH1A1 (0.46) | AVPR2ALDH1A1P2RX7AVPR1AOXTR | |
| SCHEMBL7344728 | 0.88 | ALDH1A1 (0.40) | SLC6A9ALDH1A1 | |
| SCHEMBL4682740 | 0.80 | ALDH1A1 (0.43) | AVPR2ALDH1A1P2RX7AVPR1A | |
| SCHEMBL7343891 | 0.79 | AVPR2 (0.42) | AVPR2KMT2AALDH1A1P2RX7MEN1 | |
| SCHEMBL8633381 | 0.75 | ALDH1A1 (0.39) | AVPR2KMT2AALDH1A1P2RX7MEN1 | |
| SCHEMBL4685307 | 0.71 | AVPR2 (0.45) | AVPR2ALDH1A1 | |
| SCHEMBL4680895 | 0.69 | AVPR2 (0.41) | AVPR2KMT2AALDH1A1MEN1AVPR1A | |
| SCHEMBL5480924 | 0.69 | AVPR2 (0.46) | AVPR2ALDH1A1AVPR1A | |
| SCHEMBL4684395 | 0.69 | AVPR2 (0.52) | AVPR2AVPR1AOXTR | |
| SCHEMBL4682848 | 0.69 | AVPR2 (0.45) | AVPR2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514667-B1 | Benzazepin derivatives as vasopressin antagonists | OTSUKA PHARMA CO LTD (JP) | 1995-08-09 | — | — | EP | disclosed |
| EP-0514667-A1 | Benzazepin derivatives as vasopressin antagonists | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-25 | — | — | EP | disclosed |