Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | CPT2 | P23786 | 1/20 | 0.37 |
| ▸ | CPT1A | P50416 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4682740 | 0.92 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2WDR5CPT2CPT1A | |
| SCHEMBL7336774 | 0.88 | SLC6A9 (0.36) | ALDH1A1SLC6A9 | |
| SCHEMBL7336618 | 0.81 | PKM (0.42) | ALDH1A1SMN1; SMN2WDR5MAPTLMNA | |
| SCHEMBL4697134 | 0.79 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL8634397 | 0.77 | WDR5 (0.41) | ALDH1A1SMN1; SMN2WDR5MAPTLMNA | |
| SCHEMBL7342308 | 0.76 | MAPT (0.39) | ALDH1A1SMN1; SMN2WDR5MAPTLMNA | |
| SCHEMBL4681210 | 0.75 | MAPT (0.38) | ALDH1A1SMN1; SMN2WDR5MAPTLMNA | |
| SCHEMBL4684092 | 0.74 | WDR5 (0.36) | ALDH1A1SMN1; SMN2WDR5MAPTLMNA | |
| Iodide SCHEMBL4686142 | 0.72 | AVPR2 (0.40) | ALDH1A1SMN1; SMN2WDR5MAPTLMNA | |
| SCHEMBL5474822 | 0.72 | MAPT (0.39) | ALDH1A1SMN1; SMN2WDR5MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514667-B1 | Benzazepin derivatives as vasopressin antagonists | OTSUKA PHARMA CO LTD (JP) | 1995-08-09 | — | — | EP | disclosed |
| EP-0514667-A1 | Benzazepin derivatives as vasopressin antagonists | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-25 | — | — | EP | disclosed |