Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 4/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337919 | 0.84 | YAP1 (0.53) | YAP1PPARGACEMMP9MMP8 | |
| SCHEMBL7339723 | 0.84 | MMP9 (0.44) | YAP1PPARGACEMMP9MMP8 | |
| SCHEMBL7338808 | 0.84 | YAP1 (0.45) | YAP1ACEMMP9MMP8MME | |
| SCHEMBL7344329 | 0.83 | SLC2A1 (0.47) | YAP1PPARGACEMMP9MMP8 | |
| SCHEMBL7342356 | 0.83 | YAP1 (0.51) | YAP1PPARGACEMMP9MMP8 | |
| SCHEMBL7337102 | 0.82 | YAP1 (0.47) | YAP1PPARGACEMMP9MMP8 | |
| SCHEMBL7342585 | 0.81 | YAP1 (0.47) | YAP1PPARGACEMMP9MMP8 | |
| SCHEMBL7338579 | 0.80 | UTS2R (0.53) | YAP1 | |
| SCHEMBL7345272 | 0.80 | UTS2R (0.53) | YAP1 | |
| SCHEMBL7348163 | 0.80 | PPARG (0.45) | YAP1PPARGACEMMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |