Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TCF4 | P15884 | 1/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324605 | 0.92 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2LMNAPKMHPGD | |
| SCHEMBL7325766 | 0.92 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2LMNAPKMHPGD | |
| SCHEMBL7334399 | 0.91 | GPR119 (0.62) | ALDH1A1SMN1; SMN2LMNAPKMHPGD | |
| SCHEMBL7327897 | 0.88 | IDH1 (0.57) | ALDH1A1SMN1; SMN2LMNAPKMHPGD | |
| SCHEMBL7328941 | 0.88 | F2 (0.55) | ALDH1A1SMN1; SMN2LMNAPKMHPGD | |
| SCHEMBL7324870 | 0.87 | F2 (0.59) | ALDH1A1SMN1; SMN2LMNAPKMHPGD | |
| SCHEMBL7336870 | 0.83 | IDH1 (0.61) | ALDH1A1LMNAMAPTGAANPSR1 | |
| SCHEMBL7330053 | 0.81 | F2 (0.62) | ALDH1A1SMN1; SMN2PKMF2RECQL | |
| SCHEMBL7333101 | 0.81 | FABP1 (0.59) | ALDH1A1SMN1; SMN2LMNAPKMHPGD | |
| SCHEMBL7336019 | 0.80 | BRAF (0.51) | ALDH1A1SMN1; SMN2MAPTHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |