Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | IDH1 | O75874 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | FABP1 | P07148 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330777 | 0.85 | PGR (0.58) | BRAFPGRALDH1A1HTTPFKFB3 | |
| SCHEMBL7328941 | 0.84 | F2 (0.55) | ALDH1A1HTTMAPTSMN1; SMN2 | |
| SCHEMBL7325766 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HTTMAPTPOLBFABP1 | |
| SCHEMBL7337150 | 0.80 | ALDH1A1 (0.60) | ALDH1A1HTTMAPTPOLBSMN1; SMN2 | |
| SCHEMBL7324605 | 0.79 | ALDH1A1 (0.59) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL7329316 | 0.78 | LMNA (0.59) | BRAFPGRALDH1A1POLBFABP1 | |
| SCHEMBL7334399 | 0.78 | GPR119 (0.62) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL11361752 | 0.77 | NPY5R (0.51) | ALDH1A1HTTTSHRNPY5RSMN1; SMN2 | |
| SCHEMBL9616697 | 0.77 | PGR (0.59) | BRAFPGRALDH1A1HTTPFKFB3 | |
| SCHEMBL7327897 | 0.76 | IDH1 (0.57) | BRAFIDH1ALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |