Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | PKLR | P30613 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325766 | 0.89 | ALDH1A1 (0.58) | F2KMT2AALDH1A1MEN1GAA | |
| SCHEMBL7337150 | 0.88 | ALDH1A1 (0.60) | F2ALDH1A1GAAPKMSMN1; SMN2 | |
| SCHEMBL7324605 | 0.87 | ALDH1A1 (0.59) | F2ALDH1A1GAAPKMSMN1; SMN2 | |
| SCHEMBL7334399 | 0.86 | GPR119 (0.62) | F2ALDH1A1HIF1AGAAPKM | |
| SCHEMBL7324125 | 0.85 | F2 (0.60) | F2KMT2AALDH1A1MEN1GAA | |
| SCHEMBL7336019 | 0.84 | BRAF (0.51) | ALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL7327897 | 0.83 | IDH1 (0.57) | F2KMT2AALDH1A1HIF1APKM | |
| SCHEMBL7336870 | 0.82 | IDH1 (0.61) | KMT2AALDH1A1MEN1HIF1AGAA | |
| SCHEMBL7319886 | 0.81 | LMNA (0.69) | KMT2AALDH1A1MEN1HIF1AGAA | |
| SCHEMBL8544004 | 0.79 | F2 (0.70) | F2KMT2AALDH1A1MEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |
| EP-0687253-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | Roche Diagnostics GmbH (DE) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020467-A1 | NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-15 | — | — | WO | disclosed |