Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 6/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.44 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.42 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336539 | 0.82 | CTSK (0.44) | CTSKCTSSCTSLREN | |
| SCHEMBL7344740 | 0.80 | CTSS (0.47) | CTSKCTSSCTSLCTSB | |
| SCHEMBL9610763 | 0.74 | CTSK (0.59) | CTSKCTSSCTSLCTSBREN | |
| SCHEMBL9609480 | 0.74 | CTSK (0.59) | CTSKCTSSCTSLCTSBREN | |
| SCHEMBL10630212 | 0.73 | CTSK (0.57) | CTSKCTSSCTSLCTSBREN | |
| SCHEMBL8418512 | 0.72 | REN (0.65) | CTSKCTSSCTSLCTSBREN | |
| SCHEMBL8418509 | 0.72 | CTSK (0.56) | CTSKCTSSCTSLCTSBREN | |
| SCHEMBL12890762 | 0.72 | CTSK (0.55) | CTSKCTSSCTSLCTSBREN | |
| SCHEMBL9390268 | 0.71 | CYP2D6 (0.42) | CTSKCTSSCTSLCTSBAPP | |
| SCHEMBL3499528 | 0.70 | REN (0.71) | CTSKCTSSCTSLCTSBREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416117-A | Protease inhibitor | MITSUBISHI KASEI CORPORATION (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0520427-B1 | Cyclopropenone derivatives | MITSUBISHI CHEM IND (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5328909-A | Protease inhibitors | MITSUBISHI KASEI CORPORATION (JP) | 1994-07-12 | — | — | US | disclosed |