Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.47 |
| ▸ | CTSK | P43235 | 8/20 | 0.47 |
| ▸ | CTSL | P07711 | 7/20 | 0.47 |
| ▸ | CTSB | P07858 | 4/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | LARS1 | Q9P2J5 | 2/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333112 | 0.80 | CTSS (0.48) | CTSSCTSKCTSLCTSBMMP2 | |
| SCHEMBL7333126 | 0.80 | CTSS (0.48) | CTSSCTSKCTSLCTSBMMP2 | |
| SCHEMBL5350533 | 0.80 | CTSS (0.52) | CTSSCTSKCTSLCTSBMMP2 | |
| SCHEMBL7337160 | 0.80 | CTSK (0.47) | CTSSCTSKCTSLCTSB | |
| SCHEMBL5277957 | 0.80 | CTSS (0.52) | CTSSCTSKCTSLCTSBMMP2 | |
| SCHEMBL14932686 | 0.80 | CTSS (0.52) | CTSSCTSKCTSLCTSBMMP2 | |
| SCHEMBL5350528 | 0.80 | CTSS (0.52) | CTSSCTSKCTSLCTSBMMP2 | |
| SCHEMBL7337172 | 0.78 | MMP2 (0.42) | MMP2MMP9MMP1MMP3MMP13 | |
| SCHEMBL31086879 | 0.75 | CTSL (0.62) | CTSSCTSKCTSLCTSBMMP2 | |
| SCHEMBL17789291 | 0.72 | CTSL (0.54) | CTSSCTSKCTSLCTSBMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416117-A | Protease inhibitor | MITSUBISHI KASEI CORPORATION (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0520427-B1 | Cyclopropenone derivatives | MITSUBISHI CHEM IND (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5328909-A | Protease inhibitors | MITSUBISHI KASEI CORPORATION (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0520427-A1 | Cyclopropenone derivatives | Mitsubishi Chemical Corporation (JP) | 1992-12-30 | — | — | EP | disclosed |