Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 2/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.51 |
| ▸ | ITGAV | P06756 | 1/20 | 0.51 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.50 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.50 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.50 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | IL1RN | P18510 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7341587 | 0.94 | YAP1 (0.57) | YAP1PSMB1PSMB9PSMB5PSMB10 | |
| SCHEMBL7346947 | 0.92 | PSMB1 (0.55) | YAP1PSMB1PSMB9PSMB5PSMB10 | |
| SCHEMBL7348165 | 0.85 | YAP1 (0.47) | YAP1ITGB3ITGA2BITGAVPSMB1 | |
| SCHEMBL7339667 | 0.85 | YAP1 (0.52) | YAP1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL7337028 | 0.84 | PSMB1 (0.58) | PSMB1PSMB9PSMB5PSMB10PSMB2 | |
| SCHEMBL7337924 | 0.83 | YAP1 (0.56) | YAP1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL7341943 | 0.82 | CTSS (0.53) | PSMB1PSMB9PSMB5PSMB10PSMB2 | |
| SCHEMBL7345744 | 0.82 | REN (0.57) | PSMB1PSMB9PSMB5PSMB10PSMB2 | |
| SCHEMBL7346449 | 0.82 | YAP1 (0.49) | YAP1ITGB3ITGA2BITGAVPSMB1 | |
| SCHEMBL7342359 | 0.81 | YAP1 (0.55) | YAP1PSMB5PLGPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |