Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.47 |
| ▸ | DRD3 | P35462 | 5/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7339332 | 0.99 | DRD2 (0.46) | DRD2DRD3DRD4ACHEHTR1A | |
| SCHEMBL8646170 | 0.80 | ACHE (0.60) | DRD2ACHENQO2MTNR1AMTNR1B | |
| SCHEMBL8767685 | 0.76 | DRD2 (0.70) | DRD2DRD3DRD4HTR1DHTR1B | |
| SCHEMBL8767680 | 0.76 | DRD2 (0.70) | DRD2DRD3DRD4HTR1DHTR1B | |
| Bromide SCHEMBL7333395 | 0.75 | DRD2 (0.69) | DRD2DRD3DRD4HTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL7331896 | 0.75 | DRD2 (0.69) | DRD2DRD3DRD4HTR1DHTR1B | |
| Bromide SCHEMBL7333392 | 0.75 | DRD2 (0.69) | DRD2DRD3DRD4HTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL7331890 | 0.75 | DRD2 (0.69) | DRD2DRD3DRD4HTR1DHTR1B | |
| SCHEMBL7332638 | 0.75 | ACHE (0.51) | DRD2DRD3ACHENQO2MTNR1A | |
| Hydrochloric Acid SCHEMBL7600853 | 0.74 | DRD2 (0.45) | DRD2DRD3DRD4HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781126-A2 | DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRO-NAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.p.A. (IT) | 1997-07-02 | — | — | EP | disclosed |
| WO-1996008228-A2 | DERIVATIVES OF 2-AMINO-1,2,3,4-TETRAHYDRO-NAPHTHALENE ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.P.A. (IT) | 1996-03-21 | — | — | WO | disclosed |