Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 3/20 | 0.51 |
| ▸ | REN | P00797 | 4/20 | 0.48 |
| ▸ | IL1RN | P18510 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.48 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 7/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337967 | 1.00 | YAP1 (0.51) | YAP1RENIL1RNERAP2ERAP1 | |
| SCHEMBL7341442 | 1.00 | YAP1 (0.51) | YAP1RENIL1RNERAP2ERAP1 | |
| SCHEMBL7341444 | 1.00 | YAP1 (0.51) | YAP1RENIL1RNERAP2ERAP1 | |
| SCHEMBL7345907 | 0.92 | REN (0.51) | YAP1RENIL1RNERAP2ERAP1 | |
| SCHEMBL7345901 | 0.92 | REN (0.51) | YAP1RENIL1RNERAP2ERAP1 | |
| SCHEMBL7342880 | 0.87 | CACNA1B (0.58) | YAP1RENIL1RNERAP2ERAP1 | |
| SCHEMBL7345113 | 0.87 | CACNA1B (0.58) | YAP1RENIL1RNERAP2ERAP1 | |
| SCHEMBL21023244 | 0.87 | CACNA1B (0.58) | YAP1RENIL1RNERAP2ERAP1 | |
| SCHEMBL7344934 | 0.87 | CACNA1B (0.58) | YAP1RENIL1RNERAP2ERAP1 | |
| SCHEMBL7344929 | 0.87 | CACNA1B (0.58) | YAP1RENIL1RNERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |