Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337841 | 0.96 | THRA (0.54) | ALDH1A1HTTPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL7335188 | 0.95 | THRA (0.53) | ALDH1A1HTTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL7340472 | 0.95 | THRA (0.53) | ALDH1A1HTTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL7337493 | 0.92 | KMT2A (0.52) | ALDH1A1KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL7328819 | 0.87 | KMT2A (0.56) | ALDH1A1KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL7336942 | 0.83 | KMT2A (0.46) | ALDH1A1HTTPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL7333819 | 0.83 | RAB9A (0.67) | ALDH1A1HTTPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL7333599 | 0.83 | HDAC1 (0.53) | ALDH1A1HTTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL7336971 | 0.82 | EPHX1 (0.56) | ALDH1A1HTTMAPTLMNA | |
| SCHEMBL7333221 | 0.82 | KMT2A (0.47) | POLBKMT2ASMN1; SMN2MEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475531-B1 | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same | ASAHI CHEMICAL IND (JP) | 1995-01-18 | — | — | EP | disclosed |
| EP-0475531-A1 | Benzoic acid phenylester compounds and elastase inhibiting compositions containing the same | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-03-18 | — | — | EP | disclosed |